Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 4/20 | 0.69 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.54 |
| ▸ | XIAP | P98170 | 9/20 | 0.42 |
| ▸ | FPR1 | P21462 | 2/20 | 0.38 |
| ▸ | FPR2 | P25090 | 2/20 | 0.38 |
| ▸ | NPY1R | P25929 | 2/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7794456 | 0.94 | GHSR (0.70) | GHSRAGTR1XIAPFPR1FPR2 | |
| SCHEMBL7791735 | 0.94 | GHSR (0.69) | GHSRAGTR1XIAPFPR1FPR2 | |
| SCHEMBL7791643 | 0.94 | GHSR (0.68) | GHSRAGTR1XIAPFPR1FPR2 | |
| SCHEMBL7785884 | 0.93 | GHSR (0.59) | GHSRAGTR1XIAPFPR1FPR2 | |
| SCHEMBL7796023 | 0.93 | GHSR (0.81) | GHSRAGTR1XIAPFPR1FPR2 | |
| SCHEMBL7791738 | 0.92 | GHSR (0.71) | GHSRAGTR1XIAPNPY1R | |
| SCHEMBL7791728 | 0.91 | GHSR (0.66) | GHSRAGTR1XIAPFPR1FPR2 | |
| SCHEMBL7785910 | 0.90 | GHSR (0.84) | GHSRAGTR1XIAPNPY1R | |
| SCHEMBL7794470 | 0.89 | GHSR (0.69) | GHSRAGTR1XIAPNPY1R | |
| SCHEMBL7792107 | 0.89 | GHSR (0.69) | GHSRAGTR1XIAPNPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968924-A | HAVE THE ABILITY TO STIMULATE THE RELEASE OF NATURAL OR ENDOGENOUS GROWTH HORMONE; TREATMENT OF OBESITY, OSTEOPOROSIS | MERCK & CO., INC. (US) | 1999-10-19 | — | — | US | disclosed |
| WO-1994005634-A1 | BENZO-FUSED LACTAMS PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO., INC. (US) | 1994-03-17 | — | — | WO | disclosed |