Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CETP | P11597 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7823722 | 0.81 | MEN1 (0.55) | KMT2AMEN1HTTALDH1A1SOAT1 | |
| SCHEMBL8413639 | 0.79 | CETP (0.42) | KMT2AMEN1LMNARAB9AALDH1A1 | |
| SCHEMBL8413637 | 0.79 | CETP (0.42) | KMT2AMEN1LMNARAB9AALDH1A1 | |
| SCHEMBL9901469 | 0.74 | CETP (0.67) | LMNARAB9ACETPTSHRSOAT1 | |
| SCHEMBL28063097 | 0.72 | MAPK1 (0.67) | KMT2AMEN1LMNARAB9AHTT | |
| SCHEMBL21059262 | 0.70 | SMN1; SMN2 (0.66) | LMNARAB9ANPC1ALDH1A1L3MBTL1 | |
| SCHEMBL21059252 | 0.69 | SMN1; SMN2 (0.54) | KMT2AMEN1LMNARAB9ANPC1 | |
| SCHEMBL6361102 | 0.69 | KMT2A (0.57) | KMT2AMEN1LMNARAB9ANPC1 | |
| SCHEMBL21059102 | 0.69 | SMN1; SMN2 (0.60) | LMNARAB9ANPC1ALDH1A1L3MBTL1 | |
| SCHEMBL7836111 | 0.69 | MEN1 (0.56) | KMT2AMEN1LMNARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0498721-B1 | N-substituted quinoline derivatives, process for their preparation, their use as pharmaceuticals and pharmaceutical compositions containing them | HOECHST MARION ROUSSEL INC (FR) | 1999-12-22 | — | — | EP | disclosed |
| EP-0498721-A1 | N-substituted quinoline derivatives, process for their preparation, intermediates obtained, their use as pharmaceuticals and pharmaceutical compositions containing them | ROUSSEL UCLAF (FR) | 1992-08-12 | — | — | EP | disclosed |