Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | ICMT | O60725 | 1/20 | 0.48 |
| ▸ | ALB | P02768 | 1/20 | 0.48 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.48 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7835265 | 0.83 | RAB9A (0.56) | MEN1GAAKMT2AALDH1A1HTT | |
| SCHEMBL7766895 | 0.83 | GAA (0.50) | MEN1GAAKMT2AALDH1A1NPSR1 | |
| SCHEMBL7836111 | 0.82 | MEN1 (0.56) | MEN1GAAKMT2AALDH1A1MAPT | |
| SCHEMBL8328885 | 0.81 | RAB9A (0.54) | ALDH1A1MAPTHPGDCYP2C19SMN1; SMN2 | |
| SCHEMBL8328906 | 0.81 | KMT2A (0.44) | MEN1GAAKMT2AALDH1A1HTT | |
| SCHEMBL7766898 | 0.79 | GAA (0.50) | MEN1GAAKMT2AALDH1A1NPSR1 | |
| SCHEMBL8410081 | 0.78 | ALDH1A1 (0.47) | MEN1GAAKMT2AALDH1A1NPSR1 | |
| SCHEMBL8410078 | 0.78 | ALDH1A1 (0.47) | MEN1GAAKMT2AALDH1A1NPSR1 | |
| SCHEMBL2183716 | 0.78 | ALDH1A1 (0.76) | ALDH1A1ICMTALBSOAT2SOAT1 | |
| SCHEMBL11660177 | 0.76 | ALDH1A1 (0.73) | ALDH1A1ICMTALBSOAT2SOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0498723-B1 | Nitrogen containing bicycle compounds, method for their preparation, their use as pharmaceutical and compositions containing them | AVENTIS PHARMA SA (FR) | 2001-09-19 | — | — | EP | disclosed |
| EP-0498721-B1 | N-substituted quinoline derivatives, process for their preparation, their use as pharmaceuticals and pharmaceutical compositions containing them | HOECHST MARION ROUSSEL INC (FR) | 1999-12-22 | — | — | EP | disclosed |
| EP-0498722-B1 | Bicyclic nitrogen compounds, their preparation, intermediates obtained, their use as pharmaceuticals and pharmaceutical compositions containing them | ROUSSEL UCLAF (FR) | 1997-07-30 | — | — | EP | disclosed |
| EP-0498723-A1 | Nitrogen containing bicycle compounds, method for their preparation, their use as pharmaceutical and compositions containing them | ROUSSEL UCLAF (FR) | 1992-08-12 | — | — | EP | disclosed |
| EP-0498722-A1 | Bicyclic nitrogen compounds, their preparation, intermediates obtained, their use as pharmaceuticals and pharmaceutical compositions containing them | ROUSSEL UCLAF (FR) | 1992-08-12 | — | — | EP | disclosed |
| EP-0498721-A1 | N-substituted quinoline derivatives, process for their preparation, intermediates obtained, their use as pharmaceuticals and pharmaceutical compositions containing them | ROUSSEL UCLAF (FR) | 1992-08-12 | — | — | EP | disclosed |