Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.98 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.74 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.73 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.73 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.68 |
| ▸ | THPO | P40225 | 1/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31628603 | 1.00 | SLC29A1 (0.98) | SLC29A1ADORA1ADORA3ADORA2ANFKB1 | |
| SCHEMBL6758644 | 1.00 | SLC29A1 (0.98) | SLC29A1ADORA1ADORA3ADORA2ANFKB1 | |
| SCHEMBL7183072 | 0.95 | SLC29A1 (0.88) | SLC29A1ADORA1ADORA3ADORA2ANFKB1 | |
| SCHEMBL8180763 | 0.95 | SLC29A1 (0.88) | SLC29A1ADORA1ADORA3ADORA2ANFKB1 | |
| SCHEMBL14713238 | 0.92 | SLC29A1 (0.86) | SLC29A1ADORA1ADORA3ADORA2ANFKB1 | |
| SCHEMBL20626332 | 0.92 | SLC29A1 (0.86) | SLC29A1ADORA1ADORA3ADORA2ANFKB1 | |
| SCHEMBL6758909 | 0.92 | SLC29A1 (0.86) | SLC29A1ADORA1ADORA3ADORA2ANFKB1 | |
| SCHEMBL20579790 | 0.91 | SLC29A1 (0.85) | SLC29A1ADORA1ADORA3ADORA2ANFKB1 | |
| SCHEMBL5675415 | 0.90 | SLC29A1 (0.80) | SLC29A1ADORA1ADORA3ADORA2ANFKB1 | |
| SCHEMBL10886676 | 0.90 | SLC29A1 (0.80) | SLC29A1ADORA1ADORA3ADORA2ANFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0684953-A4 | ADENOSINE KINASE INHIBITORS COMPRISING LYXOFURANOSYL DERIVATIVES. | GENSIA INC (US) | 1999-12-22 | — | — | EP | disclosed |
| EP-0684953-A1 | ADENOSINE KINASE INHIBITORS COMPRISING LYXOFURANOSYL DERIVATIVES | GENSIA, INC. (US) | 1995-12-06 | — | — | EP | disclosed |
| WO-1994018215-A1 | ADENOSINE KINASE INHIBITORS COMPRISING LYXOFURANOSYL DERIVATIVES | GENSIA, INC. (US) | 1994-08-18 | — | — | WO | disclosed |