Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 18/20 | 0.74 |
| ▸ | DRD2 | P14416 | 2/20 | 0.68 |
| ▸ | DRD3 | P35462 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20945053 | 0.86 | DRD4 (0.74) | DRD4DRD2DRD3SMN1; SMN2HRH3 | |
| SCHEMBL8327024 | 0.83 | DRD4 (0.65) | DRD4DRD2 | |
| SCHEMBL4228489 | 0.83 | DRD4 (0.65) | DRD4DRD2 | |
| SCHEMBL14155034 | 0.82 | DRD4 (0.79) | DRD4DRD2DRD3SMN1; SMN2 | |
| SCHEMBL1502307 | 0.82 | DRD4 (0.66) | DRD4DRD2DRD3 | |
| SCHEMBL4022879 | 0.82 | DRD4 (0.66) | DRD4DRD2DRD3 | |
| SCHEMBL4024819 | 0.82 | DRD4 (0.66) | DRD4DRD2DRD3 | |
| SCHEMBL1502000 | 0.81 | DRD4 (0.71) | DRD4DRD2DRD3 | |
| SCHEMBL1759405 | 0.81 | DRD4 (0.71) | DRD4DRD2DRD3 | |
| SCHEMBL10319583 | 0.81 | DRD4 (0.71) | DRD4DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760368-B1 | PYRIMIDINE DERIVATIVES | NISSHIN FLOUR MILLING CO (JP) | 1999-07-28 | — | — | EP | disclosed |
| US-5736550-A | TREATMENT OF GASTROINTESTINAL TRACT DISORDERS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1998-04-07 | — | — | US | disclosed |
| EP-0760368-A1 | NOVEL PYRIMIDINE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |