SCHEMBL1502000

SCHEMBL1502000

NCC1CN(Cc2ccccc2)CCO1

nearest known ligand 0.71

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
DRD4 P21917 18/20 0.71
CYP1A2 P05177 1/20 0.63
CYP3A4 P08684 1/20 0.63
CYP2D6 P10635 1/20 0.63
CYP2C9 P11712 1/20 0.63
DRD2 P14416 4/20 0.61
DRD3 P35462 4/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2768536 1.00 DRD4 (0.71) DRD4CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL10319583 1.00 DRD4 (0.71) DRD4CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL1759405 1.00 DRD4 (0.71) DRD4CYP1A2CYP3A4CYP2D6CYP2C9
Hydrochloric Acid SCHEMBL10670770 0.98 DRD4 (0.69) DRD4CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL8325714 0.91 DRD4 (0.60) DRD4CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL7368320 0.91 DRD4 (0.59) DRD4CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL7262675 0.88 DRD4 (0.76) DRD4CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL4228489 0.86 DRD4 (0.65) DRD4CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL8327024 0.86 DRD4 (0.65) DRD4CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL4029420 0.86 DRD4 (0.62) DRD4CYP1A2CYP3A4CYP2D6CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 225 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117434198-A Method for detecting 2-aminomethyl-4-benzyl morpholine in 2-aminomethyl-4- (4-fluorobenzyl) morpholine 黑龙江珍宝岛药业股份有限公司鸡西分公司 2024-01-23 CN claimed
EP-3604305-B1 NOVEL PYRIDONE CARBOXYLIC ACID DERIVATIVE OR SALT THEREOF WAKUNAGA PHARMA CO LTD (JP) 2024-08-28 EP disclosed
CN-117434198-A Method for detecting 2-aminomethyl-4-benzyl morpholine in 2-aminomethyl-4- (4-fluorobenzyl) morpholine 黑龙江珍宝岛药业股份有限公司鸡西分公司 2024-01-23 CN disclosed
CN-117434198-A Method for detecting 2-aminomethyl-4-benzyl morpholine in 2-aminomethyl-4- (4-fluorobenzyl) morpholine 黑龙江珍宝岛药业股份有限公司鸡西分公司 2024-01-23 CN disclosed
CN-117434198-A Method for detecting 2-aminomethyl-4-benzyl morpholine in 2-aminomethyl-4- (4-fluorobenzyl) morpholine 黑龙江珍宝岛药业股份有限公司鸡西分公司 2024-01-23 CN disclosed
US-11746091-B2 Cannabinoid receptor modulators ARENA PHARMACEUTICALS, INC. (US) 2023-09-05 US disclosed
US-20230033510-A1 Compounds and Methods for Treatment of Visceral Pain ARENA PHARMACEUTICALS, INC. 2023-02-02 US disclosed
US-11286255-B2 Pyridone carboxylic acid derivative or salt thereof WAKUNAGA PHARMACEUTICAL CO., LTD. (JP) 2022-03-29 US disclosed
US-11214548-B2 Cannabinoid receptor modulators ARENA PHARMACEUTICALS, INC. (US) 2022-01-04 US disclosed
US-20210188781-A1 CANNABINOID RECEPTOR MODULATORS ARENA PHARMACEUTICALS, INC. 2021-06-24 US disclosed
US-4889857-A BACTERICIDES; SIDE EFFECT REDUCTION YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1989-12-26 US disclosed
US-4870074-A Substituted benzamide derivatives, for enhancing gastrointestinal motility DAINIPPON PHARMACEUTICAL CO., LTD. (JP) 1989-09-26 US disclosed
EP-0311948-A2 Quinolonecarboxylic acid compounds and pharmaceutical use thereof Yoshitomi Pharmaceutical Industries, Ltd. (JP) 1989-04-19 EP disclosed
EP-0288519-A1 1-TERTIARY-ALKYL-SUBSTITUTED NAPHTHYRIDINE- AND QUINOLINE-CARBOXYLIC ACID ANTIBACTERIAL AGENTS Bristol-Myers Squibb Company (US) 1988-11-02 EP disclosed
US-4748175-A Pyrimido[5,4-B][1,4]oxazine derivatives and pharmaceutical compositions containing them CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT (HU) 1988-05-31 US disclosed
EP-0266576-A2 1-Tert-alkyl-substituted naphthyridine and quinoline carboxylic acids as antibacterial agents Bristol-Myers Squibb Company (US) 1988-05-11 EP disclosed
WO-1988002627-A1 1-TERTIARY-ALKYL-SUBSTITUTED NAPHTHYRIDINE- AND QUINOLINE-CARBOXYLIC ACID ANTIBACTERIAL AGENTS BRISTOL-MYERS COMPANY (US) 1988-04-21 WO disclosed
EP-0243959-A1 Substituted benzamide derivatives, processes for the preparation thereof, and pharmaceutical compositions containing the same Dainippon Pharmaceutical Co., Ltd. (JP) 1987-11-04 EP disclosed
CN-86108914-A Process for preparing pyrimido [5, 4-b ] [1, 4] oxazine derivatives and pharmaceutical agents containing the same CHINOIN GYOGYSZER ES VEGYESZET (HU) 1987-09-30 CN disclosed
EP-0228094-A2 Pyrimido[5,4-b][1,4]oxazine derivatives, process for their preparation, medicament containing them and intermediate pyrimido[5,4-b][1,4]oxazine derivatives CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) 1987-07-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11286255-B2 Pyridone carboxylic acid derivative or salt thereof RARA, RAB10, RABL6 DRD4 1998/4885CYP1A2 568/4885CYP3A4 2014/4885
US-11746091-B2 Cannabinoid receptor modulators CNR1, CNR2, TRPV1 DRD4 2045/4885CYP1A2 2151/4885CYP3A4 2898/4885
US-11214548-B2 Cannabinoid receptor modulators CNR1, CNR2, TRPV1 DRD4 2045/4885CYP1A2 2151/4885CYP3A4 2898/4885
US-20230033510-A1 Compounds and Methods for Treatment of Visceral Pain VIP, FABP2, FABP6 DRD4 3676/4885CYP1A2 1572/4885CYP3A4 3301/4885
US-20210188781-A1 CANNABINOID RECEPTOR MODULATORS CNR1, CNR2, TRPV1 DRD4 2045/4885CYP1A2 2151/4885CYP3A4 2898/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.