Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | OGA | O60502 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7152812 | 1.00 | TSHR (0.44) | TSHRALDH1A1CA9CA12CA1 | |
| SCHEMBL8358880 | 1.00 | TSHR (0.44) | TSHRALDH1A1CA9CA12CA1 | |
| SCHEMBL21510391 | 1.00 | TSHR (0.44) | TSHRALDH1A1CA9CA12CA1 | |
| SCHEMBL7151917 | 1.00 | TSHR (0.44) | TSHRALDH1A1CA9CA12CA1 | |
| SCHEMBL7154470 | 1.00 | TSHR (0.44) | TSHRALDH1A1CA9CA12CA1 | |
| SCHEMBL7151553 | 1.00 | TSHR (0.44) | TSHRALDH1A1CA9CA12CA1 | |
| SCHEMBL1266094 | 1.00 | TSHR (0.44) | TSHRALDH1A1CA9CA12CA1 | |
| SCHEMBL16345954 | 0.87 | CA9 (0.36) | TSHRALDH1A1CA9CA12CA1 | |
| SCHEMBL20581903 | 0.87 | ALDH1A1 (0.42) | TSHRALDH1A1CA9CA12CA1 | |
| SCHEMBL19479800 | 0.87 | CA9 (0.36) | TSHRALDH1A1CA9CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0753016-A4 | IMMUNOASSAY FOR INOSITOLS | UNIV VIRGINIA (US) | 1999-11-10 | — | — | EP | claimed |
| EP-0753016-A1 | IMMUNOASSAY FOR INOSITOLS | THE UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 1997-01-15 | — | — | EP | claimed |
| US-5525526-A | Immunoassay for inositols | THE UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 1996-06-11 | — | — | US | claimed |
| WO-1995021196-A1 | IMMUNOASSAY FOR INOSITOLS | UNIVERSITY OF VIRGINIA PATENTS FOUNDATION (US) | 1995-08-10 | — | — | WO | claimed |
| US-11322696-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2022-05-03 | — | — | US | disclosed |
| CN-109223808-B | Application of codonopsis pilosula oligosaccharide with molecular weight less than or equal to 5000Da in preparation of antioxidant active medicine for eliminating DPPH free radical | 兰州大学 | 2021-06-01 | — | — | CN | disclosed |
| CN-112321743-A | Asiatic moonseed rhizome polysaccharide and preparation method and application thereof | 山东中医药大学 | 2021-02-05 | — | — | CN | disclosed |
| EP-3526228-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2020-11-25 | — | — | EP | disclosed |
| US-20180180626-A1 | A METHOD FOR DEVELOPMENT OF RECOMBINANT PROTEINS WITH FINGERPRINT LIKE SIMILARITY TO THE REFERENCE PRODUCT | STC BIOLOGICS INC (US) | 2018-06-28 | — | — | US | disclosed |
| WO-2018069197-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2018-04-19 | — | — | WO | disclosed |
| US-9868973-B2 | Method for optimizing post-translational modifications on recombinant proteins | STC BIOLOGICS, INC. (US) | 2018-01-16 | — | — | US | disclosed |
| US-20160340706-A1 | Method for Optimizing Post-Translational Modifications on Recombinant Proteins | STC BIOLOGICS, INC. | 2016-11-24 | — | — | US | disclosed |
| EP-3094639-A1 | METHOD FOR OPTIMIZING POST-TRANSLATIONAL MODIFICATIONS ON RECOMBINANT PROTEINS | Leszcyniecka, Magdalena (US) | 2016-11-23 | — | — | EP | disclosed |
| WO-2015106276-A1 | METHOD FOR OPTIMIZING POST-TRANSLATIONAL MODIFICATIONS ON RECOMBINANT PROTEINS | LESZCYNIECKA MAGDALENA (US) | 2015-07-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11322696-B2 | Metal complexes | AP1M1, AP3M1, AP2M1 | TSHR 4729/4885ALDH1A1 2507/4885CA9 1743/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.