Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 4/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8326152 | 0.89 | MC4R (0.37) | CTSCKCNH2 | |
| SCHEMBL8326340 | 0.85 | CTSC (0.43) | CTSCKCNH2 | |
| SCHEMBL8329020 | 0.85 | KDM4E (0.37) | CTSCOPRK1 | |
| SCHEMBL8327687 | 0.83 | DPP4 (0.36) | CTSC | |
| SCHEMBL8324366 | 0.83 | CTSC (0.33) | CTSCKCNH2CDK2AKT1 | |
| SCHEMBL8330460 | 0.82 | CTSC (0.46) | CTSCKCNH2SLC6A2SLC6A4 | |
| SCHEMBL8330711 | 0.81 | EPHX1 (0.39) | CTSCKCNH2CTSS | |
| SCHEMBL8326123 | 0.73 | CTSC (0.37) | CTSCKCNH2SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL7819177 | 0.67 | CNR2 (0.44) | KCNH2CDK2AKT1SLC6A2SLC6A3 | |
| SCHEMBL6029151 | 0.67 | CHEK1 (0.39) | CTSCCDK2AKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760368-B1 | PYRIMIDINE DERIVATIVES | NISSHIN FLOUR MILLING CO (JP) | 1999-07-28 | — | — | EP | disclosed |
| EP-0760362-A1 | NOVEL DIAMINOMETHYLIDENE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |
| EP-0760368-A1 | NOVEL PYRIMIDINE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |