Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 3/20 | 0.37 |
| ▸ | CTSC | P53634 | 5/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8326340 | 0.90 | CTSC (0.43) | CTSCKCNH2 | |
| SCHEMBL8329549 | 0.89 | CTSC (0.37) | CTSCKCNH2 | |
| SCHEMBL8327687 | 0.88 | DPP4 (0.36) | CTSCSMN1; SMN2 | |
| SCHEMBL8324366 | 0.88 | CTSC (0.33) | CTSCKCNH2 | |
| SCHEMBL8330460 | 0.87 | CTSC (0.46) | CTSCKCNH2 | |
| SCHEMBL8330711 | 0.85 | EPHX1 (0.39) | CTSCKCNH2 | |
| SCHEMBL8329020 | 0.83 | KDM4E (0.37) | CTSC | |
| SCHEMBL8326123 | 0.78 | CTSC (0.37) | CTSCKCNH2 | |
| SCHEMBL8328007 | 0.72 | HTR3A (0.41) | KCNH2 | |
| SCHEMBL4591234 | 0.68 | ACACB (0.44) | CTSC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760368-B1 | PYRIMIDINE DERIVATIVES | NISSHIN FLOUR MILLING CO (JP) | 1999-07-28 | — | — | EP | disclosed |
| EP-0760362-A1 | NOVEL DIAMINOMETHYLIDENE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |
| EP-0760368-A1 | NOVEL PYRIMIDINE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |