Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.43 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.43 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.40 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8327204 | 0.91 | GRIN2D (0.43) | ACAT1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6634626 | 0.88 | LPAR1 (0.48) | LPAR1ACAT1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL8582961 | 0.79 | ACAT1 (0.37) | ACAT1SOAT1 | |
| SCHEMBL13485240 | 0.78 | ACAT1 (0.68) | ACAT1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL8586316 | 0.77 | LPAR1 (0.41) | NLRP3LPAR1 | |
| SCHEMBL8328652 | 0.76 | ACAT1 (0.69) | ACAT1SOAT1 | |
| SCHEMBL7616554 | 0.76 | ACAT1 (0.43) | ACAT1SOAT1 | |
| SCHEMBL6101574 | 0.74 | GRIN2D (0.67) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL8586795 | 0.74 | DAO (0.47) | LPAR1 | |
| SCHEMBL6635500 | 0.72 | ACAT1 (0.53) | LPAR1ACAT1SOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0947515-A1 | NOVEL NAPHTHYRIDINE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1999-10-06 | — | — | EP | disclosed |