Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.66 |
| ▸ | HTT | P42858 | 6/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.63 |
| ▸ | GALR3 | O60755 | 2/20 | 0.63 |
| ▸ | RAB9A | P51151 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | CLK1 | P49759 | 1/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.57 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | BCHE | P06276 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28270221 | 0.82 | HTT (0.81) | ALDH1A1HTTSMN1; SMN2GALR3RAB9A | |
| SCHEMBL21296571 | 0.82 | PTPN1 (0.60) | ALDH1A1HTTSMN1; SMN2GALR3RAB9A | |
| SCHEMBL7370108 | 0.81 | PTPN1 (0.67) | ALDH1A1HTTSMN1; SMN2GALR3RAB9A | |
| SCHEMBL5768189 | 0.80 | BCHE (0.60) | ALDH1A1HTTSMN1; SMN2GALR3RAB9A | |
| SCHEMBL11900441 | 0.79 | ALDH1A1 (0.70) | ALDH1A1HTTSMN1; SMN2GALR3RAB9A | |
| SCHEMBL27579461 | 0.79 | PLK4 (0.73) | ALDH1A1HTTSMN1; SMN2KDM4EPTPN1 | |
| SCHEMBL21779531 | 0.79 | DNMT1 (0.69) | ALDH1A1HTTSMN1; SMN2RAB9AKDM4E | |
| SCHEMBL21879311 | 0.78 | HTT (0.56) | ALDH1A1HTTSMN1; SMN2GALR3RAB9A | |
| SCHEMBL1902196 | 0.78 | PTPN1 (0.67) | ALDH1A1HTTSMN1; SMN2GALR3RAB9A | |
| SCHEMBL15577910 | 0.77 | KDM4E (0.53) | ALDH1A1SMN1; SMN2KDM4EPTPN1PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0556381-B1 | N-(4-PYRIDYL OR 4-QUINOLINYL) ARYLACETAMIDE PESTICIDES | DOW AGROSCIENCES LLC (US) | 1999-04-28 | — | — | EP | claimed |
| EP-0556381-B1 | N-(4-PYRIDYL OR 4-QUINOLINYL) ARYLACETAMIDE PESTICIDES | DOW AGROSCIENCES LLC (US) | 1999-04-28 | — | — | EP | disclosed |