Aminocaproic Acid

Aminocaproic Acid

SCHEMBL8329818

NCCCCCC(=O)O.NCCN

nearest known ligand 0.94

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

PLATPLG

The experimentally established mechanism targets of Aminocaproic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLG known ✓ P00747 1/20 0.94
LMNA P02545 4/20 0.94
KMT2A Q03164 3/20 0.94
ALDH1A1 P00352 3/20 0.94
THRB P10828 2/20 0.94
MEN1 O00255 2/20 0.94
ALOX15 P16050 2/20 0.94
SLC6A2 P23975 1/20 0.94
RECQL P46063 1/20 0.94
SLC6A3 Q01959 1/20 0.94
NFKB1 P19838 2/20 0.89
CYP2D6 P10635 1/20 0.89
BLM P54132 2/20 0.84
NPSR1 Q6W5P4 2/20 0.84
TSHR P16473 6/20 0.74
HDAC11 Q96DB2 6/20 0.74
GABRR3 A8MPY1 1/20 0.74
GABRP O00591 1/20 0.74
GABRD O14764 1/20 0.74
HDAC3 O15379 1/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Adipic Acid SCHEMBL8146723 1.00 LMNA (0.94) LMNAKMT2AALDH1A1THRBMEN1
Sebacic Acid SCHEMBL260910 0.97 LMNA (1.00) LMNAKMT2AALDH1A1THRBMEN1
SCHEMBL1876262 0.97 LMNA (1.00) LMNAKMT2AALDH1A1THRBMEN1
SCHEMBL2778601 0.97 LMNA (1.00) LMNAKMT2AALDH1A1THRBMEN1
Adipic Acid SCHEMBL931429 0.97 LMNA (1.00) LMNAKMT2AALDH1A1THRBMEN1
Adipic Acid SCHEMBL11332689 0.97 LMNA (1.00) LMNAKMT2AALDH1A1THRBMEN1
Aminocaproic Acid SCHEMBL21141584 0.97 LMNA (1.00) LMNAKMT2AALDH1A1THRBMEN1
12-Aminododecanoic Acid SCHEMBL20767098 0.97 LMNA (1.00) LMNAKMT2AALDH1A1THRBMEN1
Pimelic Acid SCHEMBL21465298 0.97 LMNA (1.00) LMNAKMT2AALDH1A1THRBMEN1
12-Aminododecanoic Acid SCHEMBL8973700 0.97 LMNA (1.00) LMNAKMT2AALDH1A1THRBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0542770-B1 RANDOM BIO-OLIGOMER LIBRARY, A METHOD OF SYNTHESIS THEREOF, AND A METHOD OF USE THEREOF UNIV ARIZONA (US) 1999-01-27 EP disclosed
US-5858670-A SCREENING RANDOMLY SYNTHESIZED OLIGOPEPTIDE- OR OLIGONUCLEOTIDE-SOLID PHASE LIBRARIES WITH ACCEPTOR MOLECULES (E.G. ANTIBODIES), ISOLATING SOLID PHASE SUPPORT/OLIGOMER BOUND TO MOLECULE, SEQUENCING OLIGOMER THE ARIZONA BOARD OF REGENTS (US) 1999-01-12 US disclosed
US-5650489-A SOLID PHASE SYNTHESIS OF PEPTIDES, RANDOM SEQUENCES, COMBINATORIAL CHEMISTRY THE ARIZONA BOARD OF REGENTS (US) 1997-07-22 US disclosed
US-5510240-A Method of screening a peptide library THE ARIZONA BOARD OF REGENTS (US) 1996-04-23 US disclosed
EP-0542770-A4 RANDOM BIO-OLIGOMER LIBRARY, A METHOD OF SYNTHESIS THEREOF, AND A METHOD OF USE THEREOF 1993-09-15 EP disclosed
EP-0542770-A1 RANDOM BIO-OLIGOMER LIBRARY, A METHOD OF SYNTHESIS THEREOF, AND A METHOD OF USE THEREOF ARIZONA BOARD OF REGENTS a body corporate acting on behalf of Arizona State University (US) 1993-05-26 EP disclosed
WO-1992000091-A1 RANDOM BIO-OLIGOMER LIBRARY, A METHOD OF SYNTHESIS THEREOF, AND A METHOD OF USE THEREOF BIOLIGAND, INC. (US) 1992-01-09 WO disclosed