Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 5/20 | 0.41 |
| ▸ | DRD2 | P14416 | 4/20 | 0.41 |
| ▸ | DRD3 | P35462 | 3/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7495709 | 1.00 | DRD4 (0.41) | DRD4DRD2DRD3OPRK1SLC6A2 | |
| SCHEMBL7491794 | 1.00 | DRD4 (0.41) | DRD4DRD2DRD3OPRK1SLC6A2 | |
| SCHEMBL9413099 | 0.86 | DRD4 (0.47) | DRD4DRD2DRD3LTA4HMAPT | |
| SCHEMBL9413102 | 0.86 | DRD4 (0.47) | DRD4DRD2DRD3LTA4HMAPT | |
| SCHEMBL3880873 | 0.85 | DRD2 (0.51) | DRD4DRD2DRD3OPRK1SLC6A2 | |
| SCHEMBL3880869 | 0.85 | DRD2 (0.51) | DRD4DRD2DRD3OPRK1SLC6A2 | |
| SCHEMBL30833222 | 0.85 | DRD2 (0.51) | DRD4DRD2DRD3OPRK1SLC6A2 | |
| SCHEMBL11222946 | 0.84 | MEN1 (0.48) | DRD4OPRK1MAPTADRA2BSLC6A4 | |
| SCHEMBL6632358 | 0.84 | CHRM2 (0.53) | DRD4DRD2DRD3OPRK1SLC6A2 | |
| SCHEMBL8717571 | 0.84 | CHRM2 (0.53) | DRD4DRD2DRD3OPRK1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760368-B1 | PYRIMIDINE DERIVATIVES | NISSHIN FLOUR MILLING CO (JP) | 1999-07-28 | — | — | EP | disclosed |
| EP-0760368-A1 | NOVEL PYRIMIDINE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |