Cyclohexane

Cyclohexane

SCHEMBL8329975

C1CCCCC1.CCCCC(CC)CCl

nearest known ligand 0.50

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.50
TDP1 Q9NUW8 3/20 0.50
TSHR P16473 5/20 0.48
CYP3A4 P08684 4/20 0.48
CA2 P00918 2/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
CHRM2 P08172 1/20 0.38
HTR1A P08908 1/20 0.38
ADRA2A P08913 1/20 0.38
ADORA3 P0DMS8 1/20 0.38
CHRM1 P11229 1/20 0.38
SLC6A2 P23975 1/20 0.38
SLC6A4 P31645 1/20 0.38
OPRM1 P35372 1/20 0.38
DRD3 P35462 1/20 0.38
SLC6A3 Q01959 1/20 0.38
KCNH2 Q12809 1/20 0.38
CYP2D6 P10635 1/20 0.38
ATM Q13315 1/20 0.37
LMNA P02545 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyclopentane SCHEMBL8333113 1.00 ALDH1A1 (0.50) ALDH1A1TDP1TSHRCYP3A4CA2
SCHEMBL6665960 0.93
SCHEMBL606320 0.93
SCHEMBL17937883 0.90 ALDH1A1 (0.54) ALDH1A1TDP1TSHRCYP3A4CA2
SCHEMBL888528 0.90 ALDH1A1 (0.54) ALDH1A1TDP1TSHRCYP3A4CA2
Ammonia Solution, Strong SCHEMBL9722924 0.90 ALDH1A1 (0.54) ALDH1A1TDP1TSHRCYP3A4CA2
Octane SCHEMBL8328270 0.88 ALDH1A1 (0.52) ALDH1A1TDP1TSHRCYP3A4CA2
Heptane SCHEMBL8332734 0.88 ALDH1A1 (0.52) ALDH1A1TDP1TSHRCYP3A4CA2
Dimethylamine SCHEMBL9007041 0.86 ALDH1A1 (0.54) ALDH1A1TDP1TSHRCYP3A4CA2
Alcohol SCHEMBL8828863 0.84 ALDH1A1 (0.60) ALDH1A1TDP1TSHRCYP3A4CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0707588-A4 IMPROVED ALKYLLITHIUM PROCESS FMC CORP (US) 1999-06-09 EP disclosed
EP-0707588-A1 IMPROVED ALKYLLITHIUM PROCESS FMC CORPORATION (US) 1996-04-24 EP disclosed
WO-1995001982-A1 IMPROVED ALKYLLITHIUM PROCESS FMC CORPORATION (US) 1995-01-19 WO disclosed
US-5332533-A Reacting alkyl halide with lithium metal particles in a liquid hydrocarbon solvent FMC CORPORATION (US) 1994-07-26 US disclosed