Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 2/20 | 0.37 |
| ▸ | MMP12 | P39900 | 2/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.36 |
| ▸ | HTR3B | O95264 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8326728 | 0.78 | MEN1 (0.69) | MEN1KMT2AUSP2TSHRALDH1A1 | |
| SCHEMBL8326417 | 0.76 | MEN1 (0.66) | MEN1KMT2AUSP2TSHRTDP1 | |
| SCHEMBL3290383 | 0.68 | MEN1 (0.37) | MEN1KMT2ATSHRTDP1ALDH1A1 | |
| SCHEMBL11393943 | 0.65 | MAPT (0.45) | MEN1KMT2ATDP1MMP9MMP12 | |
| SCHEMBL11592049 | 0.62 | MEN1 (0.63) | MEN1KMT2ATSHRMMP9MMP12 | |
| SCHEMBL60478 | 0.62 | MEN1 (0.63) | MEN1KMT2ATSHRMMP9MMP12 | |
| SCHEMBL31139240 | 0.62 | MEN1 (0.63) | MEN1KMT2ATSHRMMP9MMP12 | |
| SCHEMBL14720174 | 0.62 | MEN1 (0.63) | MEN1KMT2ATSHRMMP9MMP12 | |
| Ammonia Solution, Strong SCHEMBL597060 | 0.61 | MEN1 (0.61) | MEN1KMT2ATSHRMMP9MMP12 | |
| SCHEMBL10707097 | 0.61 | MEN1 (0.57) | MEN1KMT2ATSHRTDP1MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760368-B1 | PYRIMIDINE DERIVATIVES | NISSHIN FLOUR MILLING CO (JP) | 1999-07-28 | — | — | EP | disclosed |
| US-5736550-A | TREATMENT OF GASTROINTESTINAL TRACT DISORDERS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1998-04-07 | — | — | US | disclosed |
| EP-0760368-A1 | NOVEL PYRIMIDINE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |