Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NPY1R | P25929 | 1/20 | 0.42 |
| ▸ | NPY2R | P49146 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 6/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | ECE1 | P42892 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8326728 | 0.94 | MEN1 (0.69) | MEN1KMT2AL3MBTL1ALDH1A1LMNA | |
| SCHEMBL8328453 | 0.86 | KMT2A (0.67) | MEN1KMT2AL3MBTL1ALDH1A1LMNA | |
| SCHEMBL8329478 | 0.83 | MEN1 (0.62) | MEN1KMT2AALDH1A1LMNATSHR | |
| SCHEMBL8328176 | 0.74 | KMT2A (0.52) | MEN1KMT2AL3MBTL1ALDH1A1LMNA | |
| SCHEMBL11792192 | 0.70 | MEN1 (0.52) | MEN1KMT2AL3MBTL1ALDH1A1TSHR | |
| SCHEMBL28371412 | 0.67 | ALDH1A1 (0.54) | L3MBTL1ALDH1A1LMNATSHRTDP1 | |
| SCHEMBL28189582 | 0.64 | TSHR (0.52) | L3MBTL1ALDH1A1LMNATSHRTDP1 | |
| SCHEMBL21810468 | 0.64 | MEN1 (0.72) | MEN1KMT2AL3MBTL1ALDH1A1TSHR | |
| SCHEMBL1869078 | 0.63 | LMNA (0.79) | L3MBTL1ALDH1A1LMNATSHRTDP1 | |
| Dibutyl Phthalate SCHEMBL8813340 | 0.63 | TSHR (0.96) | L3MBTL1ALDH1A1LMNATSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760368-B1 | PYRIMIDINE DERIVATIVES | NISSHIN FLOUR MILLING CO (JP) | 1999-07-28 | — | — | EP | disclosed |
| US-5736550-A | TREATMENT OF GASTROINTESTINAL TRACT DISORDERS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1998-04-07 | — | — | US | disclosed |
| EP-0760368-A1 | NOVEL PYRIMIDINE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |