⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL516574 | 0.74 | KDM4E (0.34) | — | |
| SCHEMBL333613 | 0.74 | KDM4E (0.35) | — | |
| SCHEMBL143180 | 0.70 | — | — | |
| SCHEMBL2981943 | 0.67 | KDM4E (0.32) | — | |
| SCHEMBL21840732 | 0.67 | KDM4E (0.32) | — | |
| SCHEMBL729122 | 0.67 | KDM4E (0.32) | — | |
| SCHEMBL525795 | 0.67 | KDM4E (0.50) | — | |
| SCHEMBL9651 | 0.67 | KDM4E (0.32) | — | |
| SCHEMBL498059 | 0.67 | KDM4E (0.43) | — | |
| SCHEMBL1824897 | 0.64 | TSHR (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4699916-A | Substituted furazan pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 1987-10-13 | — | — | US | claimed |
| EP-0132680-B1 | SUBSTITUTED FURAZANS | BAYER AG (DE) | 1987-01-28 | — | — | EP | claimed |
| EP-0132680-A1 | Substituted furazans | BAYER AG (DE) | 1985-02-13 | — | — | EP | claimed |
| EP-1908466-B1 | SUBSTITUTED PROPANAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | DAIICHI SANKYO CO LTD (JP) | 2014-02-19 | — | — | EP | disclosed |
| US-8497397-B2 | Substituted acrylamide derivative and pharmaceutical composition comprising the same | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-07-30 | — | — | US | disclosed |
| EP-1880720-B1 | SUBSTITUTED ACRYLAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | DAIICHI SANKYO CO LTD (JP) | 2013-02-13 | — | — | EP | disclosed |
| US-8344029-B2 | Substituted propanamide derivative and pharmaceutical composition containing the same | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-01-01 | — | — | US | disclosed |
| US-20120220593-A1 | Substituted Acrylamide Derivative and Pharmaceutical Composition Comprising the Same | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-08-30 | — | — | US | disclosed |
| US-8143446-B2 | Substituted acrylamide derivative and pharmaceutical composition comprising the same | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-03-27 | — | — | US | disclosed |
| US-20090292024-A1 | SUBSTITUTED PROPANAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2009-11-26 | — | — | US | disclosed |
| US-20090118199-A1 | SUBSTITUTED ACRYLAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | DAIICHI SANKYO COMPANY , LIMITED (JP) | 2009-05-07 | — | — | US | disclosed |
| US-4853397-A | MITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1989-08-01 | — | — | US | disclosed |
| US-4826988-A | Substituted furazan pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 1989-05-02 | — | — | US | disclosed |
| EP-0189043-B1 | SUBSITUED FURAZANS | BAYER AG (DE) | 1989-03-08 | — | — | EP | disclosed |
| US-4764524-A | INSECTICIDES, ACARICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1988-08-16 | — | — | US | disclosed |
| EP-0253175-A2 | Substituted furazans | BAYER AG (DE) | 1988-01-20 | — | — | EP | disclosed |
| US-4699916-A | Substituted furazan pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 1987-10-13 | — | — | US | disclosed |
| EP-0132680-B1 | SUBSTITUTED FURAZANS | BAYER AG (DE) | 1987-01-28 | — | — | EP | disclosed |
| EP-0189043-A1 | Subsitued furazans | BAYER AG (DE) | 1986-07-30 | — | — | EP | disclosed |
| EP-0132680-A1 | Substituted furazans | BAYER AG (DE) | 1985-02-13 | — | — | EP | disclosed |