Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKAR | P32238 | 1/20 | 0.34 |
| ▸ | CCKBR | P32239 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.34 |
| ▸ | ITGAV | P06756 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4850590 | 0.94 | CCKAR (0.35) | CCKARCCKBRITGB3ITGAVHSD17B10 | |
| SCHEMBL7163716 | 0.90 | ACE (0.41) | CCKARCCKBRITGB3ITGAVHSD17B10 | |
| SCHEMBL7163504 | 0.90 | ACE (0.41) | CCKARCCKBRITGB3ITGAVHSD17B10 | |
| SCHEMBL4681624 | 0.86 | ITGB3 (0.36) | ITGB3ITGAVHSD17B10TSHRTHRB | |
| SCHEMBL4682248 | 0.86 | ITGB3 (0.36) | ITGB3ITGAVHSD17B10TSHRTHRB | |
| SCHEMBL14143519 | 0.86 | ITGB3 (0.36) | ITGB3ITGAVHSD17B10TSHRTHRB | |
| SCHEMBL14143487 | 0.86 | TSHR (0.36) | HSD17B10TSHRTHRBMEN1KMT2A | |
| SCHEMBL14181804 | 0.84 | TSHR (0.37) | HSD17B10TSHRTHRBMEN1KMT2A | |
| SCHEMBL4684103 | 0.84 | ITGB3 (0.36) | ITGB3ITGAVHSD17B10TSHRTHRB | |
| SCHEMBL7163786 | 0.84 | ITGB3 (0.36) | CCKARCCKBRITGB3ITGAVHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004072054-A1 | METHOD FOR THE PRODUCTION OF BICYCLIC AROMATIC AMINO ACIDS AND INTERMEDIATE PRODUCTS THEREOF | MERCK PATENT GMBH (DE) | 2004-08-26 | — | — | WO | disclosed |