SCHEMBL8330499

SCHEMBL8330499

CC(C)CC(N)C(=O)NN

nearest known ligand 0.56

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.56
LARS1 Q9P2J5 3/20 0.46
ANPEP P15144 6/20 0.46
RNPEP Q9H4A4 2/20 0.46
DNPEP Q9ULA0 2/20 0.46
AAK1 Q2M2I8 2/20 0.44
SLC1A3 P43003 1/20 0.43
SLC1A2 P43004 1/20 0.43
HIF1A Q16665 1/20 0.40
LAP3 P28838 2/20 0.38
ERAP1 Q9NZ08 1/20 0.38
SCN9A Q15858 3/20 0.38
CIT O14578 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19559844 1.00 SLC7A5 (0.56) SLC7A5LARS1ANPEPRNPEPDNPEP
SCHEMBL4677717 1.00 SLC7A5 (0.56) SLC7A5LARS1ANPEPRNPEPDNPEP
Bromide SCHEMBL11107160 0.98 SLC7A5 (0.54) SLC7A5LARS1ANPEPRNPEPDNPEP
SCHEMBL2715188 0.81 SLC7A5 (0.56) SLC7A5LARS1ANPEPRNPEPDNPEP
SCHEMBL836565 0.81 SLC7A5 (0.56) SLC7A5LARS1ANPEPRNPEPDNPEP
SCHEMBL246046 0.81 SLC7A5 (0.56) SLC7A5LARS1ANPEPRNPEPDNPEP
SCHEMBL1174387 0.81 SLC7A5 (0.56) SLC7A5LARS1ANPEPRNPEPDNPEP
SCHEMBL2517387 0.81 SLC7A5 (0.56) SLC7A5LARS1ANPEPRNPEPDNPEP
SCHEMBL4318870 0.81 SLC7A5 (0.56) SLC7A5LARS1ANPEPRNPEPDNPEP
SCHEMBL10296149 0.79 SLC7A5 (0.54) SLC7A5LARS1ANPEPRNPEPDNPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1744899-A Piperidine derivatives as CCR5 antagonists SMITHKLINE BEECHAM CORP (US) 2006-03-08 CN claimed
CN-1744899-A Piperidine derivatives as CCR5 antagonists SMITHKLINE BEECHAM CORP (US) 2006-03-08 CN disclosed
US-5932696-A REACTING ALKYLATED DIOL WITH CHLOROMETHYL RESIN FOLLOWED BYREACTION WITH CARBONYLDIIMIDAZOLE, SUBSEQUENT ALKYLATION AND SEQUENTIAL TREATMENT AND ACIDIFICATION WARNER-LAMBERT COMPANY (US) 1999-08-03 US disclosed
US-5869579-A CHLOROMETHYLATED DIVINYBENZENE-STYRENE RESIN MODIFIED WITH BRANCHED DIOL AND CARBONYLDIIMIDAZOLE; INTERMEDIATES WARNER-LAMBERT COMPANY (US) 1999-02-09 US disclosed
EP-0565965-B1 Benzo b thiophen-5-yl derivative and process for producing the same TOYAMA CHEMICAL CO LTD (JP) 1996-11-13 EP disclosed
US-5380878-A Benzo[b]thiophen-5-yl derivative and process for producing the same TOYAMA CHEMICAL CO., LTD. (JP) 1995-01-10 US disclosed
EP-0565965-A2 Benzo b thiophen-5-yl derivative and process for producing the same TOYAMA CHEMICAL CO., LTD. (JP) 1993-10-20 EP disclosed
US-5153274-A Reacting a carboxylated acrylonitrile-butadiene polymer and the resin product of a diamine or dihydrazide and an N,N'-bisimide of an unsaturated carboxylic acid; adhesives; composites; toughness THE SECRETARY OF STATE FOR DEFENCE IN HER MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) 1992-10-06 US disclosed
US-5087681-A Thermosetting composition; crosslinked polyimide matrix SECRETARY OF STATE FOR DEFENCE IN HER MAJESTY'S GOVERNMENT OF UNITED KINGDOM (GB) 1992-02-11 US disclosed
EP-0165812-B1 THERMOSETTING IMIDE RESIN COMPOSITIONS The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and (GB) 1988-11-09 EP disclosed
EP-0131027-B1 CURABLE THERMOSETTING PREPOLYMERISED IMIDE RESIN COMPOSITIONS The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and (GB) 1986-12-17 EP disclosed
EP-0165812-A2 Thermosetting imide resin compositions The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and (GB) 1985-12-27 EP disclosed
EP-0131027-A1 CURABLE THERMOSETTING PREPOLYMERISED IMIDE RESIN COMPOSITIONS. SECR DEFENCE BRIT (GB) 1985-01-16 EP disclosed
WO-1984002528-A1 CURABLE THERMOSETTING PREPOLYMERISED IMIDE RESIN COMPOSITIONS SECR DEFENCE BRIT (GB) 1984-07-05 WO disclosed
US-4211861-A N,N*-BISIMIDE TECHNOCHEMIE GMBH VERFAHRENSTECHNIK (DE) 1980-07-08 US disclosed