SCHEMBL4677717

SCHEMBL4677717

CC(C)C[C@H](N)C(=O)NN

nearest known ligand 0.56

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.56
LARS1 Q9P2J5 3/20 0.46
ANPEP P15144 6/20 0.46
RNPEP Q9H4A4 2/20 0.46
DNPEP Q9ULA0 2/20 0.46
AAK1 Q2M2I8 2/20 0.44
SLC1A3 P43003 1/20 0.43
SLC1A2 P43004 1/20 0.43
HIF1A Q16665 1/20 0.40
LAP3 P28838 2/20 0.38
ERAP1 Q9NZ08 1/20 0.38
SCN9A Q15858 3/20 0.38
CIT O14578 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8330499 1.00 SLC7A5 (0.56) SLC7A5LARS1ANPEPRNPEPDNPEP
SCHEMBL19559844 1.00 SLC7A5 (0.56) SLC7A5LARS1ANPEPRNPEPDNPEP
Bromide SCHEMBL11107160 0.98 SLC7A5 (0.54) SLC7A5LARS1ANPEPRNPEPDNPEP
SCHEMBL2715188 0.81 SLC7A5 (0.56) SLC7A5LARS1ANPEPRNPEPDNPEP
SCHEMBL836565 0.81 SLC7A5 (0.56) SLC7A5LARS1ANPEPRNPEPDNPEP
SCHEMBL246046 0.81 SLC7A5 (0.56) SLC7A5LARS1ANPEPRNPEPDNPEP
SCHEMBL1174387 0.81 SLC7A5 (0.56) SLC7A5LARS1ANPEPRNPEPDNPEP
SCHEMBL2517387 0.81 SLC7A5 (0.56) SLC7A5LARS1ANPEPRNPEPDNPEP
SCHEMBL4318870 0.81 SLC7A5 (0.56) SLC7A5LARS1ANPEPRNPEPDNPEP
SCHEMBL10296149 0.79 SLC7A5 (0.54) SLC7A5LARS1ANPEPRNPEPDNPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1744899-A Piperidine derivatives as CCR5 antagonists SMITHKLINE BEECHAM CORP (US) 2006-03-08 CN claimed
US-20250339567-A1 COMPOUNDS WITH IMPROVED PHARMACOKINETICS FOR IMAGING AND THERAPY OF CANCER UNIV MUENCHEN TECH (DE) 2025-11-06 US disclosed
EP-1532134-B1 NOVEL THIOPHENE ACYL HYDRAZINO DERIVATIVES, METHOD FOR PREPARING SAME, USE THEREOF AS MEDICINES, PHARMACEUTICAL COMPOSITIONS AND NOVEL USE AVENTIS PHARMA SA (FR) 2008-06-04 EP disclosed
CN-1744899-A Piperidine derivatives as CCR5 antagonists SMITHKLINE BEECHAM CORP (US) 2006-03-08 CN disclosed
EP-1532134-A1 NOVEL THIOPHENE ACYL HYDRAZINO DERIVATIVES, METHOD FOR PREPARING SAME, USE THEREOF AS MEDICINES, PHARMACEUTICAL COMPOSITIONS AND NOVEL USE Aventis Pharma S.A. (FR) 2005-05-25 EP disclosed
WO-2004007477-A1 NOVEL THIOPHENE ACYL HYDRAZINO DERIVATIVES, METHOD FOR PREPARING SAME, USE THEREOF AS MEDICINES, PHARMACEUTICAL COMPOSITIONS AND NOVEL USE AVENTIS PHARMA S.A. (FR) 2004-01-22 WO disclosed
US-5932696-A REACTING ALKYLATED DIOL WITH CHLOROMETHYL RESIN FOLLOWED BYREACTION WITH CARBONYLDIIMIDAZOLE, SUBSEQUENT ALKYLATION AND SEQUENTIAL TREATMENT AND ACIDIFICATION WARNER-LAMBERT COMPANY (US) 1999-08-03 US disclosed
US-5869579-A CHLOROMETHYLATED DIVINYBENZENE-STYRENE RESIN MODIFIED WITH BRANCHED DIOL AND CARBONYLDIIMIDAZOLE; INTERMEDIATES WARNER-LAMBERT COMPANY (US) 1999-02-09 US disclosed
EP-0565965-B1 Benzo b thiophen-5-yl derivative and process for producing the same TOYAMA CHEMICAL CO LTD (JP) 1996-11-13 EP disclosed
US-5380878-A Benzo[b]thiophen-5-yl derivative and process for producing the same TOYAMA CHEMICAL CO., LTD. (JP) 1995-01-10 US disclosed
US-5153274-A Reacting a carboxylated acrylonitrile-butadiene polymer and the resin product of a diamine or dihydrazide and an N,N'-bisimide of an unsaturated carboxylic acid; adhesives; composites; toughness THE SECRETARY OF STATE FOR DEFENCE IN HER MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) 1992-10-06 US disclosed
US-5087681-A Thermosetting composition; crosslinked polyimide matrix SECRETARY OF STATE FOR DEFENCE IN HER MAJESTY'S GOVERNMENT OF UNITED KINGDOM (GB) 1992-02-11 US disclosed
EP-0165812-B1 THERMOSETTING IMIDE RESIN COMPOSITIONS The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and (GB) 1988-11-09 EP disclosed
EP-0131027-B1 CURABLE THERMOSETTING PREPOLYMERISED IMIDE RESIN COMPOSITIONS The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and (GB) 1986-12-17 EP disclosed
EP-0165812-A2 Thermosetting imide resin compositions The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and (GB) 1985-12-27 EP disclosed
EP-0131027-A1 CURABLE THERMOSETTING PREPOLYMERISED IMIDE RESIN COMPOSITIONS. SECR DEFENCE BRIT (GB) 1985-01-16 EP disclosed
US-4459227-A Para-hydroxyphenylhydrazines as in situ precursors of iminoquinones and quinones DUKE UNIVERSITY (US) 1984-07-10 US disclosed
WO-1984002528-A1 CURABLE THERMOSETTING PREPOLYMERISED IMIDE RESIN COMPOSITIONS SECR DEFENCE BRIT (GB) 1984-07-05 WO disclosed
US-4438249-A Biodegradable polyurethane urea acyl semicarbazides for the manufacture of biodegradable alloimplants LIPATOVA TATYANA E (SU) 1984-03-20 US disclosed
US-4211861-A N,N*-BISIMIDE TECHNOCHEMIE GMBH VERFAHRENSTECHNIK (DE) 1980-07-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250339567-A1 COMPOUNDS WITH IMPROVED PHARMACOKINETICS FOR IMAGING AND THERAPY OF CANCER RXFP2, XPNPEP2, ANTXR2 SLC7A5 484/4885LARS1 1324/4885ANPEP 27/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.