Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.54 |
| ▸ | GSK3B | P49841 | 3/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4770340 | 0.94 | GSK3B (0.57) | HAO1GSK3BHDAC1HDAC8KMT2A | |
| SCHEMBL11373953 | 0.84 | HAO1 (0.50) | HAO1GSK3BHDAC1HDAC8KMT2A | |
| SCHEMBL2739301 | 0.83 | MAPT (0.63) | HAO1GSK3BKMT2AMEN1PTPN1 | |
| SCHEMBL8987897 | 0.79 | SMN1; SMN2 (0.68) | HAO1GSK3BHDAC1HDAC8KMT2A | |
| SCHEMBL17148448 | 0.78 | KMT2A (0.52) | KMT2AMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL5255481 | 0.78 | GSK3B (0.52) | HAO1GSK3BHDAC1HDAC8KMT2A | |
| SCHEMBL11161484 | 0.78 | KMT2A (0.57) | HAO1GSK3BHDAC1HDAC8KMT2A | |
| SCHEMBL5255476 | 0.78 | GSK3B (0.55) | HAO1GSK3BHDAC1HDAC8KMT2A | |
| SCHEMBL2452141 | 0.78 | HDAC1 (0.57) | HAO1GSK3BHDAC1HDAC8KMT2A | |
| SCHEMBL9422398 | 0.77 | ALDH1A1 (0.50) | KMT2AMEN1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999001446-A1 | NOVEL 4-HYDROXY-2H-1-(THIO)PYRAN-2-ONES DERIVATIVES AND THEIR USE AS RAT POISON | LIPHATEC (FR) | 1999-01-14 | — | — | WO | disclosed |