SCHEMBL8330801

SCHEMBL8330801

O=C(O)Oc1cccc(C(=O)c2cccc(OC(=O)O)c2)c1

nearest known ligand 0.61

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.61
TDP1 Q9NUW8 1/20 0.61
L3MBTL1 Q9Y468 1/20 0.61
STS P08842 8/20 0.59
SRD5A2 P31213 1/20 0.53
ALDH1A1 P00352 1/20 0.52
PBRM1 Q86U86 1/20 0.52
ELANE P08246 1/20 0.50
AKR1C3 P42330 1/20 0.50
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
NPC1 O15118 1/20 0.47
RAB9A P51151 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL474776 0.98 ATM (0.65) ATMTDP1L3MBTL1STSSRD5A2
SCHEMBL361122 0.94 ELANE (0.59) ATMTDP1L3MBTL1STSSRD5A2
SCHEMBL9419481 0.88 STS (0.49) ATMTDP1L3MBTL1STSSRD5A2
SCHEMBL5314324 0.86 ELANE (0.70) ATMTDP1L3MBTL1STSSRD5A2
SCHEMBL27812147 0.86 TDP1 (0.61) ATMTDP1L3MBTL1STSSRD5A2
Benzophenone SCHEMBL16721022 0.85 ELANE (0.67) ATMTDP1L3MBTL1STSSRD5A2
SCHEMBL1040127 0.84 KMT2A (0.62) ATMTDP1L3MBTL1AKR1C3MEN1
SCHEMBL1543224 0.82 ELANE (0.42) ATMTDP1L3MBTL1STSSRD5A2
SCHEMBL7086600 0.82 TDP1 (0.55) ATMTDP1L3MBTL1STSSRD5A2
SCHEMBL11002454 0.82 AKR1C3 (0.75) ATMTDP1L3MBTL1STSSRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0344099-B1 A polyester and an article made of the same SEIKISUI CHEMICAL CO LTD (JP) 1995-04-12 EP claimed
EP-3512905-A1 METHOD FOR PRODUCING A POLYBENZAZOL POLYMER (P) BASF SE (DE) 2019-07-24 EP disclosed
WO-2018050489-A1 METHOD FOR PRODUCING A POLYBENZAZOL POLYMER (P) BASF SE (DE) 2018-03-22 WO disclosed
EP-0547502-B2 Hardenable binder and its process of manufacture HOECHST AG (DE) 1999-02-10 EP disclosed
EP-0821042-A2 Elastic auto-crosslinking binder for coating of cans and sheets, its production and use Vianova Resins GmbH (DE) 1998-01-28 EP disclosed
EP-0591762-A1 Process for the preparation of polycarbonates and polyestercarbonates BAYER AG (DE) 1994-04-13 EP disclosed
EP-0547502-A1 Hardenable binder and its process of manufacture HOECHST AKTIENGESELLSCHAFT (DE) 1993-06-23 EP disclosed