SCHEMBL7086600

SCHEMBL7086600

C=CC(=O)Oc1cccc(C(=O)c2ccccc2)c1

nearest known ligand 0.55

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.55
ATM Q13315 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
STS P08842 4/20 0.54
SRD5A2 P31213 1/20 0.49
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
NPC1 O15118 1/20 0.47
RAB9A P51151 1/20 0.47
PBRM1 Q86U86 1/20 0.47
ALDH1A1 P00352 1/20 0.47
ELANE P08246 2/20 0.46
AKR1C3 P42330 1/20 0.46
THRB P10828 1/20 0.45
AKT1 P31749 1/20 0.44
MAPT P10636 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6058212 0.86 AKR1C3 (0.58) KMT2ANPC1RAB9AAKR1C3
SCHEMBL29472341 0.86 AKR1C3 (0.58) KMT2ANPC1RAB9AAKR1C3
SCHEMBL11216577 0.84 ELANE (0.45) TDP1ATML3MBTL1MEN1KMT2A
SCHEMBL39494 0.84 ELANE (0.65) STSSRD5A2MEN1KMT2ANPC1
SCHEMBL474776 0.84 ATM (0.65) TDP1ATML3MBTL1STSSRD5A2
SCHEMBL8330801 0.82 ATM (0.61) TDP1ATML3MBTL1STSSRD5A2
SCHEMBL421454 0.82 KMT2A (0.56) TDP1MEN1KMT2ANPC1RAB9A
SCHEMBL5245757 0.81 L3MBTL1 (0.57) TDP1ATML3MBTL1STSSRD5A2
SCHEMBL5314324 0.81 ELANE (0.70) TDP1ATML3MBTL1STSSRD5A2
SCHEMBL27812147 0.81 TDP1 (0.61) TDP1ATML3MBTL1STSSRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3951520-A Color imaging using the Christiansen effect E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-04-20 US claimed
US-20030162892-A1 Coating system for veneered wood based on polyurethane dispersions method for the production and use thereof CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2003-08-28 US disclosed
US-4269933-A PHOTOLITHOGRAPHY; POSITIVE AND NEGATIVE IMAGES; POLYMERIZATION OF A UNSATURATED POLYESTER USING A PHOTOSENSITIVE FREE RADICAL SYSTEM E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-05-26 US disclosed
US-4251619-A Process for forming photo-polymeric image KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1981-02-17 US disclosed
US-4198242-A Photopolymerizable composition containing an o-nitroaromatic compound as photoinhibitor E. I. DU PONT DE NEMOURS AND COMPANY (US) 1980-04-15 US disclosed
US-4168981-A Bis(substituted amino)sulfides as reversible inhibitor sources for photopolymerization E. I. DU PONT DE NEMOURS AND COMPANY (US) 1979-09-25 US disclosed
US-4168982-A Photopolymerizable compositions containing nitroso dimers to selectively inhibit thermal polymerization E. I. DU PONT DE NEMOURS AND COMPANY (US) 1979-09-25 US disclosed
US-4029505-A PHOTOPOLYMERIZABLE LAYER OF UNSATURATED COMPOUND, DINITROSO COMPOUND, AND FREE-RADICAL GENERATOR E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-06-14 US disclosed
US-4008083-A Stabilization of color images formed by photomodulation of the Christiansen effect E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-02-15 US disclosed
US-3951520-A Color imaging using the Christiansen effect E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-04-20 US disclosed