Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | METAP1 | P53582 | 1/20 | 0.43 |
| ▸ | KDM5A | P29375 | 3/20 | 0.42 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.42 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.42 |
| ▸ | KDM4A | O75164 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11223456 | 1.00 | CYP1A2 (0.45) | CYP1A2METAP1KDM5APHF8KDM2A | |
| SCHEMBL16732010 | 0.98 | MAPT (0.42) | CYP1A2METAP1KDM5APHF8KDM2A | |
| SCHEMBL23833698 | 0.92 | SIGMAR1 (0.48) | CYP1A2METAP1KDM5APHF8KDM2A | |
| SCHEMBL6192922 | 0.89 | CYP1A2 (0.44) | CYP1A2METAP1KDM5APHF8KDM2A | |
| SCHEMBL28014935 | 0.87 | METAP1 (0.50) | CYP1A2METAP1KDM5APHF8KDM2A | |
| SCHEMBL28875946 | 0.85 | METAP1 (0.48) | CYP1A2METAP1KDM5APHF8KDM2A | |
| SCHEMBL28875904 | 0.85 | METAP1 (0.48) | CYP1A2METAP1KDM5APHF8KDM2A | |
| SCHEMBL28315546 | 0.85 | METAP1 (0.48) | CYP1A2METAP1KDM5APHF8KDM2A | |
| SCHEMBL28315755 | 0.85 | METAP1 (0.48) | CYP1A2METAP1KDM5APHF8KDM2A | |
| SCHEMBL28315748 | 0.85 | METAP1 (0.48) | CYP1A2METAP1KDM5APHF8KDM2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5908863-A | ANTIGROWTH AGENT FOR BONES | DOMPE' S.P.A. (IT) | 1999-06-01 | — | — | US | disclosed |
| EP-0792878-A2 | Geminal carboxylic acids and esters thereof, pharmaceutical formulations containing them useful in the treatment of bone dysmetabolism | Dompé S.P.A. (IT) | 1997-09-03 | — | — | EP | disclosed |