Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.47 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7465159 | 0.72 | HTR2C (0.44) | NAAAMAOAFAAH | |
| SCHEMBL29187194 | 0.68 | GRM5 (0.54) | GRM5MAOA | |
| SCHEMBL20939195 | 0.68 | GRM5 (0.40) | GRM5MAOAFAAH | |
| SCHEMBL20925715 | 0.68 | GRM5 (0.54) | GRM5MAOAMAPK14HTR2ACXCR2 | |
| SCHEMBL20917395 | 0.68 | GRM5 (0.54) | GRM5NAAAMAOAMAPK14CXCR2 | |
| SCHEMBL28175144 | 0.66 | GRM5 (0.51) | GRM5MAOAHTR2A | |
| SCHEMBL5966248 | 0.66 | GRM5 (0.50) | GRM5MAOAHTR2A | |
| SCHEMBL102791 | 0.65 | GRM5 (0.50) | GRM5HTR2A | |
| SCHEMBL20917220 | 0.65 | GRM5 (0.38) | GRM5PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL20917218 | 0.65 | GRM5 (0.38) | GRM5PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996030344-A9 | PYRIMIDINE COMPOUNDS | — | 1999-02-11 | — | — | WO | disclosed |
| EP-0817773-A2 | PYRIMIDINE COMPOUNDS | THE SECRETARY OF STATE FOR DEFENCE (GB) | 1998-01-14 | — | — | EP | disclosed |