Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 15/20 | 0.72 |
| ▸ | RARA | P10276 | 13/20 | 0.72 |
| ▸ | RARG | P13631 | 11/20 | 0.72 |
| ▸ | RXRA | P19793 | 1/20 | 0.53 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.53 |
| ▸ | DHODH | Q02127 | 1/20 | 0.48 |
| ▸ | PTGES | O14684 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8330106 | 0.90 | RARB (0.61) | RARBRARARARGRXRANR2E1 | |
| SCHEMBL6239917 | 0.84 | RARB (1.00) | RARBRARARARGRXRANR2E1 | |
| SCHEMBL8632968 | 0.83 | RARA (0.75) | RARBRARARARGRXRANR2E1 | |
| SCHEMBL7627172 | 0.82 | RARA (0.64) | RARBRARARARGRXRANR2E1 | |
| SCHEMBL4652302 | 0.82 | RARB (0.74) | RARBRARARARGRXRANR2E1 | |
| SCHEMBL6234835 | 0.82 | RARA (0.81) | RARBRARARARG | |
| SCHEMBL6238148 | 0.82 | RARB (0.77) | RARBRARARARGRXRANR2E1 | |
| SCHEMBL8331499 | 0.80 | RARB (0.58) | RARBRARARARGRXRANR2E1 | |
| SCHEMBL6237886 | 0.80 | RARA (1.00) | RARBRARARARGRXRANR2E1 | |
| SCHEMBL4757231 | 0.79 | RARA (1.00) | RARBRARARARGRXRANR2E1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958954-A | 2,2-DIALKYL-4-ARYL-SUBSTITUTED BENZOPYRAN AND BENZOTHIOPYRAN DERIVATIVES | ALLERGAN SALES, INC. (US) | 1999-09-28 | — | — | US | disclosed |
| US-5952345-A | RETINOID ACID RECEPTOR ANTAGONIST; A DERIVATIVES OF ARYL-SUBSTITUTED AND ARYL (3-OXO-1-PROPENLY)-SUBSTITUTED BENZOPYRAN, BENZOTHIOPYRAN, 1,2-DIHYDROQUINOLINE; PREVENTING TOXICITY OR SIDE EFFECTS CAUSED BY RETINOIDS OR VITAMIN A | ALLERGAN SALES, INC. (US) | 1999-09-14 | — | — | US | disclosed |
| US-5877207-A | SKIN DISORDERS; ANTICARCINOGENIC AGENTS | ALLERGAN SALES, INC. (US) | 1999-03-02 | — | — | US | disclosed |
| US-5776699-A | MEASURING GENE EXPRESSION | ALLERGAN, INC. (US) | 1998-07-07 | — | — | US | disclosed |