SCHEMBL8332181

SCHEMBL8332181

CCc1cccc(N(C(N)=NC)c2cc(Cl)ccc2Cl)c1

nearest known ligand 0.58

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 19/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8198033 0.81 SIGMAR1 (0.46) SIGMAR1
SCHEMBL8332178 0.78 SIGMAR1 (0.63) SIGMAR1
SCHEMBL27498292 0.77 SIGMAR1 (0.64) SIGMAR1
SCHEMBL6717383 0.73 SIGMAR1 (1.00) SIGMAR1
SCHEMBL27519227 0.73 SIGMAR1 (0.59) SIGMAR1
SCHEMBL6727820 0.72 SIGMAR1 (1.00) SIGMAR1
Hydrochloric Acid SCHEMBL7204348 0.72 SIGMAR1 (1.00) SIGMAR1
Hydrochloric Acid SCHEMBL7201782 0.72 SIGMAR1 (1.00) SIGMAR1
SCHEMBL27560537 0.71 SIGMAR1 (0.57) SIGMAR1
SCHEMBL27482601 0.71 SIGMAR1 (0.66) SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1999002145-A1 COMBINATION DRUG THERAPIES COMPRISING AMINOGLYCOSIDE ANTIBIOTICS AND N,N'-DISUBSTITUTED GUANIDINES CAMBRIDGE NEUROSCIENCE, INC. (US) 1999-01-21 WO disclosed