Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 11/20 | 0.70 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.59 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.46 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.46 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8332073 | 1.00 | ADK (0.70) | ADKADORA1PRKAG1PRKAA1PRKAB1 | |
| SCHEMBL8333393 | 0.93 | ADK (0.79) | ADK | |
| SCHEMBL8975564 | 0.89 | ADK (0.88) | ADK | |
| SCHEMBL8332958 | 0.87 | ADK (0.70) | ADK | |
| SCHEMBL8975258 | 0.85 | ADK (0.80) | ADK | |
| SCHEMBL8975175 | 0.84 | ADK (0.68) | ADK | |
| SCHEMBL8330949 | 0.84 | ADK (0.80) | ADKADORA1 | |
| SCHEMBL8333662 | 0.82 | ADK (0.67) | ADK | |
| SCHEMBL8328731 | 0.82 | ADK (1.00) | ADK | |
| SCHEMBL8328727 | 0.82 | ADK (1.00) | ADK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0684953-A4 | ADENOSINE KINASE INHIBITORS COMPRISING LYXOFURANOSYL DERIVATIVES. | GENSIA INC (US) | 1999-12-22 | — | — | EP | disclosed |
| US-5506347-A | ADENOSINE KINASE INHIBITOR | GENSIA, INC. (US) | 1996-04-09 | — | — | US | disclosed |
| EP-0684953-A1 | ADENOSINE KINASE INHIBITORS COMPRISING LYXOFURANOSYL DERIVATIVES | GENSIA, INC. (US) | 1995-12-06 | — | — | EP | disclosed |
| WO-1994018215-A1 | ADENOSINE KINASE INHIBITORS COMPRISING LYXOFURANOSYL DERIVATIVES | GENSIA, INC. (US) | 1994-08-18 | — | — | WO | disclosed |