SCHEMBL8332902

SCHEMBL8332902

O=C(CCCCCCCCCCC(=O)OCC(O)CO)OCC(O)CO

nearest known ligand 0.82

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.82
KDM4E B2RXH2 1/20 0.82
DUSP3 P51452 1/20 0.82
MEN1 O00255 1/20 0.82
KMT2A Q03164 1/20 0.82
DGKA P23743 1/20 0.68
FAAH O00519 2/20 0.55
MAPT P10636 1/20 0.53
ENPP2 Q13822 4/20 0.51
PRKCA P17252 3/20 0.51
PRKCE Q02156 1/20 0.51
PRKCQ Q04759 1/20 0.51
PRKCD Q05655 1/20 0.51
LPAR6 P43657 1/20 0.51
LPAR1 Q92633 1/20 0.51
LPAR4 Q99677 1/20 0.51
LPAR5 Q9H1C0 1/20 0.51
LPAR2 Q9HBW0 1/20 0.51
LPAR3 Q9UBY5 1/20 0.51
CNR2 P34972 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL380177 1.00 LMNA (0.82) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL20624 1.00 LMNA (0.82) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL839526 1.00 LMNA (0.82) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL10797197 1.00 LMNA (0.82) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL822924 0.98 KDM4E (0.79) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL270755 0.98 KDM4E (0.79) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL25356276 0.94 KDM4E (0.74) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL127956 0.94 KDM4E (0.74) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL3505466 0.94 KDM4E (0.74) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL25355124 0.94 KDM4E (0.74) LMNAKDM4EDUSP3MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3950018-A1 HYDROPHOBIC TISSUE ADHESIVES Massachusetts Institute Of Technology (US) 2022-02-09 EP disclosed
EP-3004221-B1 HYDROPHOBIC TISSUE ADHESIVES MASSACHUSETTS INST TECHNOLOGY (US) 2021-10-27 EP disclosed
US-9724447-B2 Hydrophobic tissue adhesives MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2017-08-08 US disclosed
EP-3004221-A1 HYDROPHOBIC TISSUE ADHESIVES Massachusetts Institute of Technology (US) 2016-04-13 EP disclosed
US-20150191607-A1 Anti-fouling Paints and Coatings REACTIVE SURFACES, LTD (US) 2015-07-09 US disclosed
WO-2014190302-A1 HYDROPHOBIC TISSUE ADHESIVES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2014-11-27 WO disclosed
US-20140348896-A1 Hydrophobic Tissue Adhesives MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2014-11-27 US disclosed
WO-1998048768-A9 COMPOSITIONS FOR COSMETIC APPLICATIONS MEDLOGIC GLOBAL CORP (US) 1999-03-25 WO disclosed