Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 20/20 | 0.75 |
| ▸ | ITGAV | P06756 | 20/20 | 0.75 |
| ▸ | ITGB6 | P18564 | 18/20 | 0.75 |
| ▸ | ITGB5 | P18084 | 13/20 | 0.75 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.58 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6267787 | 0.87 | ITGB3 (0.83) | ITGB3ITGAVITGB6ITGB5ITGA2B | |
| SCHEMBL2836956 | 0.85 | ITGB3 (1.00) | ITGB3ITGAVITGB6ITGB5ITGA2B | |
| SCHEMBL6265063 | 0.79 | ITGB3 (0.68) | ITGB3ITGAVITGB6ITGB5ITGA2B | |
| SCHEMBL8336926 | 0.79 | ITGB3 (0.70) | ITGB3ITGAVITGB6ITGB5ITGA2B | |
| SCHEMBL8326227 | 0.79 | ITGB3 (0.68) | ITGB3ITGAVITGB6ITGB5ITGA2B | |
| SCHEMBL2838879 | 0.77 | ITGB3 (0.82) | ITGB3ITGAVITGB6ITGB5ITGA2B | |
| SCHEMBL2833650 | 0.77 | ITGB3 (0.84) | ITGB3ITGAVITGB6ITGB5ITGA2B | |
| SCHEMBL2840996 | 0.77 | ITGB3 (0.82) | ITGB3ITGAVITGB6ITGB5ITGA2B | |
| SCHEMBL2838535 | 0.77 | ITGB3 (0.84) | ITGB3ITGAVITGB6ITGB5ITGA2B | |
| SCHEMBL2838532 | 0.76 | ITGB3 (0.79) | ITGB3ITGAVITGB6ITGB5ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004058254-A1 | HETEROARYLALKANOIC ACIDS AS INTEGRIN RECEPTOR ANTAGONISTS | PHARMACIA CORPORATION (US) | 2004-07-15 | — | — | WO | disclosed |