⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL835052 | 0.77 | — | — | |
| SCHEMBL834980 | 0.74 | — | — | |
| SCHEMBL2561945 | 0.71 | — | — | |
| SCHEMBL1578441 | 0.69 | — | — | |
| SCHEMBL114589 | 0.67 | — | — | |
| SCHEMBL9556853 | 0.67 | — | — | |
| SCHEMBL1722946 | 0.65 | — | — | |
| SCHEMBL63219 | 0.64 | ENPEP (0.30) | — | |
| SCHEMBL2566012 | 0.64 | — | — | |
| SCHEMBL2566450 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230014137-A1 | COMPOUND HAVING LYSOPHOSPHATIDIC ACID RECEPTOR AGONIST ACTIVITY AND PHARMACEUTICAL USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2023-01-19 | — | — | US | disclosed |
| EP-3131893-B1 | POLYCYCLIC HERG ACTIVATORS | NOVARTIS AG (CH) | 2020-02-12 | — | — | EP | disclosed |
| EP-3131893-A1 | POLYCYCLIC HERG ACTIVATORS | Novartis AG (CH) | 2017-02-22 | — | — | EP | disclosed |
| US-20160108025-A1 | POLYCYCLIC HERG ACTIVATORS | NOVARTIS AG | 2016-04-21 | — | — | US | disclosed |
| US-9255093-B2 | Polycyclic HERG activators | NOVARTIS AG (CH) | 2016-02-09 | — | — | US | disclosed |
| US-20150299181-A1 | POLYCYCLIC HERG ACTIVATORS | NOVARTIS AG (CH) | 2015-10-22 | — | — | US | disclosed |
| WO-2015161052-A1 | POLYCYCLIC HERG ACTIVATORS | NOVARTIS AG (CH) | 2015-10-22 | — | — | WO | disclosed |
| EP-1908466-B1 | SUBSTITUTED PROPANAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | DAIICHI SANKYO CO LTD (JP) | 2014-02-19 | — | — | EP | disclosed |
| US-8497397-B2 | Substituted acrylamide derivative and pharmaceutical composition comprising the same | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-07-30 | — | — | US | disclosed |
| EP-1880720-B1 | SUBSTITUTED ACRYLAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | DAIICHI SANKYO CO LTD (JP) | 2013-02-13 | — | — | EP | disclosed |
| EP-1908466-A1 | SUBSTITUTED PROPANAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | Daiichi Sankyo Company, Limited (JP) | 2008-04-09 | — | — | EP | disclosed |
| EP-1880720-A1 | SUBSTITUTED ACRYLAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Daiichi Sankyo Company, Limited (JP) | 2008-01-23 | — | — | EP | disclosed |
| US-6444616-B1 | HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-09-03 | — | — | US | disclosed |
| US-6130225-A | Substituted p-trifluoromethylphenyluracils | BAYER AKTIENGESELLSCHAFT (DE) | 2000-10-10 | — | — | US | disclosed |
| EP-0923562-A1 | SUBSTITUTED P-TRIFLUOROMETHYLPHENYLURACILS | BAYER AG (DE) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998006706-A1 | SUBSTITUTED P-TRIFLUOROMETHYLPHENYLURACILS | BAYER AKTIENGESELLSCHAFT (DE) | 1998-02-19 | — | — | WO | disclosed |
| EP-0486937-B1 | Hydrazone derivatives, processes for production thereof, and uses thereof | NIHON NOHYAKU CO LTD (JP) | 1995-03-22 | — | — | EP | disclosed |
| US-5358965-A | Agricultural and horticultural insecticides, activity against moths and beetles | NIHON NOHYAKU CO., LTD. (JP) | 1994-10-25 | — | — | US | disclosed |
| US-5304573-A | Insecticides | NIHON NOHYAKU CO., LTD. (JP) | 1994-04-19 | — | — | US | disclosed |
| EP-0486937-A1 | Hydrazone derivatives, processes for production thereof, and uses thereof | NIHON NOHYAKU CO., LTD. (JP) | 1992-05-27 | — | — | EP | disclosed |