Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.77 |
| ▸ | LMNA | P02545 | 5/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | TP53 | P04637 | 3/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25938113 | 1.00 | L3MBTL1 (0.77) | L3MBTL1LMNASMN1; SMN2TP53ALOX15 | |
| SCHEMBL30557537 | 1.00 | L3MBTL1 (0.77) | L3MBTL1LMNASMN1; SMN2TP53ALOX15 | |
| SCHEMBL9892884 | 0.94 | L3MBTL1 (0.68) | L3MBTL1LMNASMN1; SMN2TP53ALOX15 | |
| SCHEMBL23418024 | 0.84 | L3MBTL1 (0.67) | L3MBTL1LMNASMN1; SMN2NPSR1NPC1 | |
| SCHEMBL3282254 | 0.84 | L3MBTL1 (0.64) | L3MBTL1LMNASMN1; SMN2NPSR1NPC1 | |
| SCHEMBL29919455 | 0.84 | L3MBTL1 (0.67) | L3MBTL1LMNASMN1; SMN2NPSR1NPC1 | |
| SCHEMBL25333202 | 0.84 | SMN1; SMN2 (0.61) | L3MBTL1LMNASMN1; SMN2TP53ALOX15 | |
| SCHEMBL13256799 | 0.84 | L3MBTL1 (0.77) | L3MBTL1LMNASMN1; SMN2TP53NPSR1 | |
| SCHEMBL16238648 | 0.84 | L3MBTL1 (0.68) | L3MBTL1LMNATP53ALOX15TSHR | |
| SCHEMBL16238573 | 0.84 | L3MBTL1 (0.68) | L3MBTL1LMNASMN1; SMN2NPSR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023144793-A1 | POL THETA INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2023-08-03 | — | — | WO | disclosed |
| EP-0797447-A4 | HUMAN CANCER INHIBITORY PENTAPEPTIDE HETEROCYCLIC AND HALOPHENYL AMIDES | UNIV ARIZONA (US) | 1999-09-29 | — | — | EP | disclosed |
| EP-0797447-A1 | HUMAN CANCER INHIBITORY PENTAPEPTIDE HETEROCYCLIC AND HALOPHENYL AMIDES | ARIZONA BOARD OF REGENTS (US) | 1997-10-01 | — | — | EP | disclosed |
| US-5663149-A | ANTICARCINOGENIC AGENTS RELATED TO DOLASTATIN | ARIZONA BOARD OF REGENTS ACTING ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 1997-09-02 | — | — | US | disclosed |
| WO-1996018408-A1 | HUMAN CANCER INHIBITORY PENTAPEPTIDE HETEROCYCLIC AND HALOPHENYL AMIDES | ARIZONA BOARD OF REGENTS (US) | 1996-06-20 | — | — | WO | disclosed |