Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.70 |
| ▸ | ABCB1 | P08183 | 7/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | DRD2 | P14416 | 1/20 | 0.60 |
| ▸ | DRD1 | P21728 | 1/20 | 0.60 |
| ▸ | DRD3 | P35462 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8336525 | 0.99 | MAPT (0.69) | MAPTABCB1ALDH1A1KDM4EMEN1 | |
| SCHEMBL8337024 | 0.99 | MAPT (0.68) | MAPTABCB1ALDH1A1KDM4EMEN1 | |
| SCHEMBL8336449 | 0.93 | DRD2 (0.69) | MAPTABCB1ALDH1A1KDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL8336215 | 0.92 | DRD2 (0.67) | MAPTABCB1KDM4EMEN1KMT2A | |
| SCHEMBL8337315 | 0.92 | DRD1 (0.71) | MAPTABCB1ALDH1A1KDM4EMEN1 | |
| SCHEMBL11806753 | 0.89 | MAPT (0.74) | MAPTABCB1ALDH1A1KDM4EMEN1 | |
| SCHEMBL11336084 | 0.87 | MAPT (0.76) | MAPTABCB1ALDH1A1KDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL15514017 | 0.83 | MAPT (0.70) | MAPTABCB1ALDH1A1KDM4EMEN1 | |
| SCHEMBL1334318 | 0.82 | MAPT (0.65) | MAPTABCB1ALDH1A1KDM4EMEN1 | |
| SCHEMBL1335907 | 0.82 | MAPT (0.65) | MAPTABCB1ALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5948796-A | OSTEOPOROSIS, CANCER, CARDIOVASCULAR DISORDERS | ELI LILLY AND COMPANY (US) | 1999-09-07 | — | — | US | disclosed |