Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Dronabinol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 known ✓ | P21554 | 9/20 | 0.70 |
| ▸ | CNR2 | P34972 | 16/20 | 0.70 |
| ▸ | ABHD12 | Q8N2K0 | 3/20 | 0.70 |
| ▸ | ABHD6 | Q9BV23 | 3/20 | 0.70 |
| ▸ | FAAH | O00519 | 2/20 | 0.70 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.70 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.70 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.70 |
| ▸ | LDHA | P00338 | 1/20 | 0.70 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.70 |
| ▸ | GPR183 | P32249 | 1/20 | 0.70 |
| ▸ | DRD3 | P35462 | 1/20 | 0.70 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.70 |
| ▸ | GPR18 | Q14330 | 1/20 | 0.70 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.61 |
| ▸ | HTR1A | P08908 | 1/20 | 0.61 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.61 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.61 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.61 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dronabinol SCHEMBL29410178 | 0.84 | CNR2 (1.00) | CNR2CNR1ABHD12ABHD6FAAH | |
| Dronabinol SCHEMBL3686519 | 0.84 | CNR2 (1.00) | CNR2CNR1ABHD12ABHD6FAAH | |
| Dronabinol SCHEMBL11375978 | 0.84 | CNR2 (1.00) | CNR2CNR1ABHD12ABHD6FAAH | |
| Dronabinol SCHEMBL1227386 | 0.84 | CNR2 (1.00) | CNR2CNR1ABHD12ABHD6FAAH | |
| Dronabinol SCHEMBL13214137 | 0.84 | CNR2 (1.00) | CNR2CNR1ABHD12ABHD6FAAH | |
| Dronabinol SCHEMBL24702729 | 0.84 | CNR2 (1.00) | CNR2CNR1ABHD12ABHD6FAAH | |
| Dronabinol SCHEMBL13394311 | 0.84 | CNR2 (1.00) | CNR2CNR1ABHD12ABHD6FAAH | |
| Dronabinol SCHEMBL4609 | 0.84 | CNR2 (1.00) | CNR2CNR1ABHD12ABHD6FAAH | |
| Dronabinol SCHEMBL22705549 | 0.84 | CNR2 (1.00) | CNR2CNR1ABHD12ABHD6FAAH | |
| Dronabinol SCHEMBL29422026 | 0.84 | CNR2 (1.00) | CNR2CNR1ABHD12ABHD6FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-209656722-U | A kind of device for collecting liquid sample | HANGZHOU BIOTEST BIOTECH CO LTD | 2019-11-19 | — | — | CN | disclosed |
| CN-209656723-U | A kind of device for collecting liquid sample | HANGZHOU BIOTEST BIOTECH CO LTD | 2019-11-19 | — | — | CN | disclosed |
| CN-110441091-A | A kind of device collected and detect analyte in fluid sample | ZHEJIANG ORIENT GENE BIOTECH CO LTD | 2019-11-12 | — | — | CN | disclosed |
| CN-209559909-U | A kind of device for collecting liquid sample | HANGZHOU BIOTEST BIOTECH CO LTD | 2019-10-29 | — | — | CN | disclosed |
| CN-209559910-U | A kind of lid | HANGZHOU BIOTEST BIOTECH CO LTD | 2019-10-29 | — | — | CN | disclosed |
| CN-110161272-A | A kind of collecting chamber | 杭州博拓生物科技股份有限公司 | 2019-08-23 | — | — | CN | disclosed |
| CN-110161266-A | A method of collecting liquid sample | 杭州博拓生物科技股份有限公司 | 2019-08-23 | — | — | CN | disclosed |
| CN-110161271-A | A kind of lid | 杭州博拓生物科技股份有限公司 | 2019-08-23 | — | — | CN | disclosed |
| CN-110161273-A | The collection and detection device of sample | 杭州博拓生物科技股份有限公司 | 2019-08-23 | — | — | CN | disclosed |
| CN-110161265-A | A kind of device for collecting liquid sample | 杭州博拓生物科技股份有限公司 | 2019-08-23 | — | — | CN | disclosed |
| CN-105044320-B | Detection apparatus for testing to-be-analyzed substance in liquid sample | 艾博生物医药(杭州)有限公司 | 2017-02-22 | — | — | CN | disclosed |
| CN-104122385-B | A kind of detection device and using method thereof | 艾博生物医药(杭州)有限公司 | 2016-09-07 | — | — | CN | disclosed |
| CN-105866400-A | Device for rapidly detecting and preserving samples and usage method thereof | 艾博生物医药(杭州)有限公司 | 2016-08-17 | — | — | CN | disclosed |
| EP-0836407-A4 | DERMAL PATCH WITHOUT A SEPARATE ABSORBENT MATERIAL | SUDOR PARTNERS (US) | 1999-09-22 | — | — | EP | disclosed |
| EP-0836407-A1 | DERMAL PATCH WITHOUT A SEPARATE ABSORBENT MATERIAL | SUDOR PARTNERS (US) | 1998-04-22 | — | — | EP | disclosed |
| WO-1996039923-A1 | DERMAL PATCH WITHOUT A SEPARATE ABSORBENT MATERIAL | SUDOR PARTNERS (US) | 1996-12-19 | — | — | WO | disclosed |
| EP-0676051-A1 | METHOD AND APPARATUS FOR DETERMINATION OF CHEMICAL SPECIES IN PERSPIRATION | SUDOR PARTNERS (US) | 1995-10-11 | — | — | EP | disclosed |
| WO-1994014062-A1 | METHOD AND APPARATUS FOR DETERMINATION OF CHEMICAL SPECIES IN PERSPIRATION | SUDOR PARTNERS (US) | 1994-06-23 | — | — | WO | disclosed |
| EP-0543867-A1 | METHOD AND APPARATUS FOR DETERMINATION OF CHEMICAL SPECIES IN BODY FLUID. | SUDOR PARTNERS (US) | 1993-06-02 | — | — | EP | disclosed |
| WO-1992003731-A1 | METHOD AND APPARATUS FOR DETERMINATION OF CHEMICAL SPECIES IN BODY FLUID | SUDOR PARTNERS (US) | 1992-03-05 | — | — | WO | disclosed |