Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 11/20 | 0.45 |
| ▸ | CNR2 | P34972 | 5/20 | 0.35 |
| ▸ | CNR1 | P21554 | 4/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.34 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5357251 | 0.87 | FBP1 (0.39) | FBP1CNR2CNR1GRM2 | |
| SCHEMBL5362792 | 0.81 | FBP1 (0.41) | FBP1CNR2CNR1 | |
| SCHEMBL5367608 | 0.67 | FBP1 (0.39) | FBP1GRM2FDPS | |
| SCHEMBL12264875 | 0.67 | CNR2 (0.57) | CNR2CNR1 | |
| SCHEMBL4955833 | 0.65 | FBP1 (0.65) | FBP1 | |
| SCHEMBL5362049 | 0.63 | FBP1 (0.36) | FBP1FDPS | |
| SCHEMBL10773261 | 0.62 | BRD4 (0.47) | FDPS | |
| SCHEMBL9645945 | 0.62 | INPPL1 (0.61) | — | |
| SCHEMBL13741964 | 0.61 | FBP1 (1.00) | FBP1 | |
| SCHEMBL30983966 | 0.61 | MEN1 (0.46) | FBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998039344-A9 | NOVEL PURINE INHIBITORS OF FRUCTOSE-1,6-BISPHOSPHATASE | — | 1999-01-21 | — | — | WO | disclosed |
| WO-1998039344-A1 | NOVEL PURINE INHIBITORS OF FRUCTOSE-1,6-BISPHOSPHATASE | METABASIS THERAPEUTICS, INC. (US) | 1998-09-11 | — | — | WO | disclosed |