Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 7/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7181126 | 0.84 | MAOB (0.46) | MAPTLMNAATMSMN1; SMN2KEAP1 | |
| SCHEMBL9203891 | 0.81 | MAPT (0.73) | MAPTLMNAATMSMN1; SMN2KEAP1 | |
| SCHEMBL9203900 | 0.81 | MAPT (0.73) | MAPTLMNAATMSMN1; SMN2KEAP1 | |
| SCHEMBL7180028 | 0.79 | MAPT (0.43) | MAPTLMNAATMSMN1; SMN2KEAP1 | |
| SCHEMBL7185139 | 0.78 | LMNA (0.47) | MAPTLMNAATMSMN1; SMN2KEAP1 | |
| SCHEMBL7191503 | 0.78 | ABCG2 (0.57) | MAPTLMNAATMSMN1; SMN2KEAP1 | |
| SCHEMBL7191499 | 0.78 | ABCG2 (0.57) | MAPTLMNAATMSMN1; SMN2KEAP1 | |
| SCHEMBL9204757 | 0.76 | MAPT (0.60) | MAPTLMNAATMSMN1; SMN2KEAP1 | |
| SCHEMBL7184382 | 0.75 | LMNA (0.51) | MAPTLMNAATMSMN1; SMN2KEAP1 | |
| SCHEMBL7184448 | 0.75 | ABCG2 (0.44) | MAPTLMNAATMSMN1; SMN2KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5985935-A | PARASITICIDES OR BACTERICIDES | STATENS SERUMINSTITUT (DK) | 1999-11-16 | — | — | US | disclosed |