Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 3/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8334253 | 1.00 | MAPT (0.50) | MAPTRAB9ANPC1KMT2AMAOB | |
| SCHEMBL8146385 | 0.79 | MAPT (0.62) | MAPTRAB9ANPC1KMT2AMAOB | |
| SCHEMBL28140741 | 0.78 | MAPT (0.52) | MAPTRAB9ANPC1KMT2AMAOB | |
| SCHEMBL8159019 | 0.78 | MAPT (0.54) | MAPTRAB9ANPC1KMT2AMAOB | |
| SCHEMBL7187442 | 0.73 | MAOB (0.51) | MAPTMAOBMAOALMNASMN1; SMN2 | |
| SCHEMBL7187449 | 0.73 | MAOB (0.51) | MAPTMAOBMAOALMNASMN1; SMN2 | |
| SCHEMBL7186566 | 0.72 | ABCG2 (0.55) | MAPTRAB9AMAOBMAOALMNA | |
| SCHEMBL7186568 | 0.72 | ABCG2 (0.55) | MAPTRAB9AMAOBMAOALMNA | |
| SCHEMBL8160069 | 0.71 | MAPT (0.52) | MAPTRAB9ANPC1KMT2AMAOB | |
| SCHEMBL7180100 | 0.71 | ABCG2 (0.49) | MAPTRAB9ANPC1MAOBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5985935-A | PARASITICIDES OR BACTERICIDES | STATENS SERUMINSTITUT (DK) | 1999-11-16 | — | — | US | disclosed |