Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 3/20 | 0.34 |
| ▸ | CTSL | P07711 | 2/20 | 0.34 |
| ▸ | CTSB | P07858 | 2/20 | 0.34 |
| ▸ | CTSD | P07339 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 10/20 | 0.34 |
| ▸ | F2 | P00734 | 2/20 | 0.34 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | PLAT | P00750 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4702614 | 0.87 | F10 (0.37) | F10F2KLKB1ELANEPLAT | |
| SCHEMBL4702621 | 0.87 | F10 (0.37) | F10F2KLKB1ELANEPLAT | |
| SCHEMBL4704572 | 0.85 | GAA (0.39) | GAACTSKCTSLCTSBCTSD | |
| SCHEMBL8336602 | 0.81 | GAA (0.38) | GAACTSKCTSLCTSBCTSD | |
| SCHEMBL8334904 | 0.81 | GAA (0.38) | GAACTSKCTSLCTSBCTSD | |
| SCHEMBL8334598 | 0.80 | GAA (0.40) | GAACTSKCTSLCTSBCTSD | |
| SCHEMBL4706424 | 0.73 | F10 (0.70) | F10F2KLKB1PLAT | |
| SCHEMBL4706427 | 0.73 | F10 (0.70) | F10F2KLKB1PLAT | |
| SCHEMBL6564079 | 0.70 | GAA (0.40) | GAACTSKF10F2TSHR | |
| SCHEMBL4705673 | 0.70 | F10 (0.40) | F10F2KLKB1ELANEPLAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004052851-A1 | PYRROLYDIN-2-ONE DERIVATIVES AS INHIBITORS OF THROMBIN AND FACTOR XA | GLAXO GROUP LIMITED (GB) | 2004-06-24 | — | — | WO | disclosed |