Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7477312 | 0.91 | HTR1D (0.83) | HTR1DHTR1B | |
| SCHEMBL8332389 | 0.89 | HTR1D (0.81) | HTR1DHTR1B | |
| SCHEMBL8915888 | 0.89 | HTR1D (1.00) | HTR1DHTR1B | |
| SCHEMBL8399430 | 0.88 | HTR1D (0.79) | HTR1DHTR1B | |
| SCHEMBL8403541 | 0.88 | HTR1D (0.79) | HTR1DHTR1B | |
| SCHEMBL8427610 | 0.88 | HTR1D (0.78) | HTR1DHTR1B | |
| SCHEMBL8431783 | 0.88 | HTR1D (0.78) | HTR1DHTR1B | |
| SCHEMBL7480569 | 0.88 | HTR1D (0.78) | HTR1DHTR1B | |
| SCHEMBL7475617 | 0.87 | HTR1D (0.81) | HTR1DHTR1B | |
| SCHEMBL7479900 | 0.87 | HTR1D (0.77) | HTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5981529-A | Substituted indolylpropyl-piperazine derivatives as 5-HT1D α agonists | MERCK SHARP & DOHME LIMITED (GB) | 1999-11-09 | — | — | US | disclosed |
| EP-0854714-A1 | SUBSTITUTED INDOLYLPROPYL-PIPERAZINE DERIVATIVES AS 5-HT 1DALPHA? AGONISTS | MERCK SHARP & DOHME LTD. (GB) | 1998-07-29 | — | — | EP | disclosed |
| WO-1997011695-A1 | SUBSTITUTED INDOLYLPROPYL-PIPERAZINE DERIVATIVES AS 5-HT1DALPHA AGONISTS | MERCK SHARP & DOHME LIMITED (GB) | 1997-04-03 | — | — | WO | disclosed |