SCHEMBL8334694

SCHEMBL8334694

CCCCOC(=O)[C@H](Cc1ncc(-c2ccccc2)o1)NC(=O)C1(C[C@@H](CCC)C(=O)O)CCCC1

nearest known ligand 0.59

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MME P08473 20/20 0.59
NPPA P01160 3/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6807607 0.95 MME (0.61) MMENPPA
SCHEMBL6803882 0.90 MME (0.57) MMENPPA
SCHEMBL6256064 0.90 MME (0.71) MMENPPA
SCHEMBL6808326 0.88 MME (0.51) MMENPPA
SCHEMBL6808331 0.88 MME (0.51) MMENPPA
SCHEMBL6808651 0.88 MME (0.65) MMENPPA
SCHEMBL6531175 0.84 MME (0.61) MMENPPA
SCHEMBL6807888 0.84 MME (0.55) MMENPPA
SCHEMBL6531169 0.84 MME (0.61) MMENPPA
SCHEMBL6530515 0.84 MME (0.61) MMENPPA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004056787-A1 CYCLOPENTYL GLUTARAMIDES AND THEIR USE AS NEUTRAL ENDOPEPTIDASE INHIBITORS PFIZER LIMITED (GB) 2004-07-08 WO disclosed