SCHEMBL6531175

SCHEMBL6531175

COCCC(CC1(C(=O)N[C@@H](Cc2ncc(-c3ccccc3)o2)C(=O)OCC(C)C)CCCC1)C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MME P08473 17/20 0.61
NPPA P01160 6/20 0.61
MMP1 P03956 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6530515 1.00 MME (0.61) MMENPPAMMP1
SCHEMBL6530510 1.00 MME (0.61) MMENPPAMMP1
SCHEMBL6531169 1.00 MME (0.61) MMENPPAMMP1
Potassium Ion SCHEMBL6508837 0.93 MME (0.57) MMENPPAMMP1
Water SCHEMBL6528919 0.93 MME (0.56) MMENPPAMMP1
SCHEMBL8275076 0.92 MME (0.56) MMENPPAMMP1
SCHEMBL6255996 0.91 MME (0.73) MMENPPAMMP1
SCHEMBL6812430 0.89 MME (0.60) MMENPPAMMP1
SCHEMBL6807770 0.88 MME (0.60) MMENPPAMMP1
SCHEMBL6807772 0.88 MME (0.60) MMENPPAMMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005123702-A1 NEUTRAL ENDOPEPTIDASE INHIBITOR POLYMORPH PFIZER LIMITED (GB) 2005-12-29 WO disclosed