Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.64 |
| ▸ | DPP8 | Q6V1X1 | 10/20 | 0.64 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.58 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.58 |
| ▸ | ACE | P12821 | 1/20 | 0.58 |
| ▸ | HTR2A | P28223 | 1/20 | 0.58 |
| ▸ | FAP | Q12884 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5487180 | 0.87 | DPP4 (0.62) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL5935884 | 0.86 | DPP4 (0.70) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL5230936 | 0.76 | DPP4 (1.00) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL8324895 | 0.76 | DPP4 (0.61) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL6853393 | 0.75 | DPP4 (0.78) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL7902672 | 0.75 | DPP4 (0.78) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL14267898 | 0.75 | DPP4 (0.78) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL5495778 | 0.75 | DPP4 (0.71) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL1050284 | 0.74 | KCNH2 (0.70) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL8332960 | 0.74 | DPP4 (0.65) | DPP4DPP8DPP9DPP7ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004058266-A1 | 3-AMINO-4-PHENYLBUTANOIC ACID DERIVATIVES AS DIPEPTIDYL PEPTIDASE INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES | MERCK & CO., INC. (US) | 2004-07-15 | — | — | WO | disclosed |