Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4979588 | 0.84 | TSHR (0.45) | ALDH1A1MAPTTSHRNPSR1HTT | |
| SCHEMBL4979578 | 0.77 | TSHR (0.60) | ALDH1A1MAPTTSHRNPSR1HTT | |
| SCHEMBL4980203 | 0.76 | NPSR1 (0.43) | ALDH1A1MAPTTSHRNPSR1HTT | |
| Hydrochloric Acid SCHEMBL4985012 | 0.75 | TSHR (0.58) | ALDH1A1MAPTTSHRNPSR1HTT | |
| SCHEMBL4979590 | 0.69 | SIGMAR1 (0.48) | ALDH1A1MAPTTSHRNPSR1KMT2A | |
| SCHEMBL4981135 | 0.68 | CYP2C9 (0.35) | ALDH1A1MAPTTSHRNPSR1KMT2A | |
| SCHEMBL9891809 | 0.68 | TSHR (0.66) | ALDH1A1MAPTTSHRNPSR1HTT | |
| SCHEMBL18509379 | 0.68 | TSHR (0.57) | ALDH1A1MAPTTSHRNPSR1HTT | |
| SCHEMBL27921803 | 0.67 | MEN1 (0.57) | MAPTNPSR1KMT2AMEN1GAA | |
| SCHEMBL5923635 | 0.67 | TSHR (0.46) | ALDH1A1MAPTTSHRNPSR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999002145-A1 | COMBINATION DRUG THERAPIES COMPRISING AMINOGLYCOSIDE ANTIBIOTICS AND N,N'-DISUBSTITUTED GUANIDINES | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1999-01-21 | — | — | WO | disclosed |