Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 18/20 | 0.82 |
| ▸ | DPP7 | Q9UHL4 | 13/20 | 0.57 |
| ▸ | DPP8 | Q6V1X1 | 8/20 | 0.57 |
| ▸ | DPP9 | Q86TI2 | 7/20 | 0.57 |
| ▸ | FAP | Q12884 | 2/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.56 |
| ▸ | HRH2 | P25021 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2606781 | 0.88 | DPP4 (0.66) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL3129828 | 0.88 | DPP4 (0.66) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL3129738 | 0.88 | DPP4 (0.66) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL5787207 | 0.88 | DPP4 (0.66) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL3140707 | 0.88 | DPP4 (0.65) | DPP4DPP7DPP8DPP9FAP | |
| Hydrochloric Acid SCHEMBL2107366 | 0.87 | DPP4 (0.65) | DPP4DPP7DPP8DPP9FAP | |
| Hydrochloric Acid SCHEMBL2107365 | 0.87 | DPP4 (0.65) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL2606773 | 0.85 | DPP4 (0.62) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL2606751 | 0.85 | DPP4 (0.62) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL4327505 | 0.85 | DPP4 (0.62) | DPP4DPP7DPP8DPP9FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004050022-A2 | PHENYLALANINE DERIVATIVES AS DIPEPTIDYL PEPTIDASE INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES | MERCK & CO., INC. (US) | 2004-06-17 | — | — | WO | disclosed |