Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINA6 | P08185 | 5/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | PGR | P06401 | 3/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.50 |
| ▸ | SHBG | P04278 | 2/20 | 0.50 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.50 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | AR | P10275 | 2/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6828230 | 0.87 | SERPINA6 (0.69) | SERPINA6CYP3A4ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL16741271 | 0.86 | SERPINA6 (0.67) | SERPINA6CYP3A4ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL7705294 | 0.86 | SHBG (0.61) | SERPINA6CYP3A4ALDH1A1LMNAMAPT | |
| SCHEMBL29496903 | 0.86 | SHBG (0.61) | SERPINA6CYP3A4ALDH1A1LMNAMAPT | |
| SCHEMBL5552057 | 0.86 | SHBG (0.61) | SERPINA6CYP3A4ALDH1A1LMNAMAPT | |
| SCHEMBL28509865 | 0.82 | SERPINA6 (0.62) | SERPINA6CYP3A4ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL8209833 | 0.78 | CYP19A1 (0.59) | SERPINA6ALDH1A1SMN1; SMN2LMNATSHR | |
| SCHEMBL4265197 | 0.78 | SERPINA6 (1.00) | SERPINA6CYP3A4ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL17831160 | 0.78 | SERPINA6 (1.00) | SERPINA6CYP3A4ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL17831140 | 0.78 | SERPINA6 (1.00) | SERPINA6CYP3A4ALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998055153-A9 | NON-STEROIDAL RADIOLABELED AGONIST/ANTAGONIST COMPOUNDS AND THEIR USE IN PROSTATE CANCER IMAGING | UNIV TENNESSEE RES CORP (US) | 1999-04-01 | — | — | WO | disclosed |
| WO-1998055153-A1 | NON-STEROIDAL RADIOLABELED AGONIST/ANTAGONIST COMPOUNDS AND THEIR USE IN PROSTATE CANCER IMAGING | THE UNIVERSITY OF TENNESSEE RESEARCH CORPORATION (US) | 1998-12-10 | — | — | WO | disclosed |