SCHEMBL8335357

SCHEMBL8335357

CCN(CC(=O)O)c1nc(Cl)nc(NC(C)C)n1

nearest known ligand 0.60

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GAA P10253 5/20 0.60
SMN1; SMN2 Q16637 3/20 0.60
TDP1 Q9NUW8 1/20 0.47
KMT2A Q03164 2/20 0.44
MEN1 O00255 1/20 0.44
ALDH1A1 P00352 7/20 0.42
MAPT P10636 2/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
TP53 P04637 1/20 0.37
KDM4E B2RXH2 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29370231 0.85 GAA (0.60) GAASMN1; SMN2TDP1KMT2AMEN1
SCHEMBL133242 0.85 GAA (0.60) GAASMN1; SMN2TDP1KMT2AMEN1
SCHEMBL8333505 0.83 GAA (0.51) GAASMN1; SMN2TDP1KMT2AMAPT
SCHEMBL11837479 0.79 GAA (0.56) GAASMN1; SMN2TDP1KMT2AMEN1
SCHEMBL11261210 0.76 GAA (0.60) GAASMN1; SMN2TDP1KMT2AMEN1
SCHEMBL5266118 0.74 CYP2C9 (0.45) GAASMN1; SMN2TDP1ALDH1A1L3MBTL1
SCHEMBL11691073 0.74 ALDH1A1 (0.52) GAASMN1; SMN2TDP1KMT2AMEN1
SCHEMBL9333796 0.74 GAA (0.57) GAASMN1; SMN2TDP1KMT2AMEN1
SCHEMBL11683284 0.73 GAA (0.50) GAASMN1; SMN2TDP1KMT2AMEN1
SCHEMBL27346633 0.72 TDP1 (0.38) GAASMN1; SMN2TDP1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5952264-A APPLYING ONE OF THE FUNGUS COCHLIOBOLUS INTERMEDIUS AND CURVULARIA INTERMEDIA TO PEST GRASS IN AGRICULTURAL CROP LOUISIANA TECH UNIVERSITY FOUNDATION, INC. 1999-09-14 US disclosed
US-5635448-A 3-SUBSTITUTED PHENYLPYRAZOLE DERIVATIVES ASAMURA PATENT OFFICE (JP) 1997-06-03 US disclosed
US-5424271-A Applying herbicides along with mold strain MITSUI TOATSU CHEMICALS, INC. (JP) 1995-06-13 US disclosed
EP-0619946-A1 Herbicidal composition for upland farming and weeding method NIHON NOHYAKU CO., LTD. (JP) 1994-10-19 EP disclosed
EP-0464416-B1 New strains of Drechslera spp., and weed control agents and weed control compositions containing the same MITSUI TOATSU CHEMICALS (JP) 1994-09-07 EP disclosed
US-5332573-A Herbicides MITSUI TOATSU CHEMICALS INC. (JP) 1994-07-26 US disclosed
CN-1058508-A This new bacterial strain of mould (Drechslera) Pseudomonas of moral and contain the weed control agent of this bacterial strain and weeds control mix preparation MITSUI TOATSU CHEMICALS (JP) 1992-02-12 CN disclosed
EP-0464416-A2 New strains of Drechslera spp., and weed control agents and weed control compositions containing the same MITSUI TOATSU CHEMICALS, Inc. (JP) 1992-01-08 EP disclosed