Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6719258 | 0.87 | KMT2A (0.51) | LMNAALOX12HTTKMT2AALDH1A1 | |
| SCHEMBL6715738 | 0.87 | KMT2A (0.53) | LMNAALOX12HTTKMT2AALDH1A1 | |
| SCHEMBL6717393 | 0.84 | ALDH1A1 (0.52) | LMNAALOX12HTTKMT2AALDH1A1 | |
| SCHEMBL6718586 | 0.83 | SMN1; SMN2 (0.54) | LMNAALOX12HTTKMT2AALDH1A1 | |
| SCHEMBL6825413 | 0.81 | MAPT (0.60) | LMNAKMT2AALDH1A1MAPTTDP1 | |
| SCHEMBL6714000 | 0.81 | ALDH1A1 (0.57) | LMNAALOX12ALDH1A1NPSR1MAPT | |
| SCHEMBL6727004 | 0.81 | MAPT (0.51) | LMNAALOX12HTTKMT2AALDH1A1 | |
| SCHEMBL6723832 | 0.80 | SMN1; SMN2 (0.54) | LMNAHTTKMT2AALDH1A1NPSR1 | |
| SCHEMBL6723442 | 0.80 | MEN1 (0.58) | LPAR1LMNAHTTKMT2AALDH1A1 | |
| SCHEMBL6715739 | 0.79 | MEN1 (0.56) | LMNAHTTKMT2AALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004022528-A2 | ARYLGLYCINE DERIVATIVES AND THEIR USE AS GLYCINE TRANSPORT INHIBITORS | NPS ALLELIX CORP. (CA) | 2004-03-18 | — | — | WO | disclosed |