Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | ERN1 | O75460 | 2/20 | 0.35 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MYC | P01106 | 1/20 | 0.33 |
| ▸ | ATIC | P31939 | 1/20 | 0.33 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 2/20 | 0.33 |
| ▸ | RAD1 | O60671 | 1/20 | 0.33 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | FABP4 | P15090 | 1/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2543853 | 0.82 | TTR (0.40) | TTRTDP1CYP1A2AURKAAURKB | |
| SCHEMBL10480252 | 0.82 | ERN1 (0.55) | TTRTDP1CYP1A2ERN1PGAM1 | |
| SCHEMBL8341041 | 0.82 | TDP1 (0.39) | TDP1CYP1A2PGAM1AURKAAURKB | |
| SCHEMBL438031 | 0.82 | TTR (0.40) | TTRTDP1CYP1A2AURKAAURKB | |
| SCHEMBL15000 | 0.82 | TDP1 (0.44) | TTRTDP1CYP1A2PGAM1ALDH1A1 | |
| SCHEMBL29361804 | 0.82 | TDP1 (0.44) | TTRTDP1CYP1A2PGAM1ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL18492496 | 0.81 | TTR (0.39) | TTRTDP1CYP1A2AURKAAURKB | |
| Ethylene SCHEMBL28187575 | 0.81 | TTR (0.39) | TTRTDP1CYP1A2AURKAAURKB | |
| SCHEMBL332205 | 0.80 | TDP1 (0.43) | TTRTDP1CYP1A2PGAM1ALDH1A1 | |
| SCHEMBL6131308 | 0.80 | TDP1 (0.43) | TTRTDP1CYP1A2PGAM1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999005986-A1 | IMPROVED DENTAL FLOSS | WHITEHILL ORAL TECHNOLOGIES, INC. (US) | 1999-02-11 | — | — | WO | disclosed |