Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propane SCHEMBL15303565 | 0.86 | GRIK1 (0.32) | ALDH1A1TSHRKDM4E | |
| Butane SCHEMBL10765613 | 0.84 | GRIK1 (0.33) | TSHRKDM4E | |
| SCHEMBL462908 | 0.84 | TSHR (0.34) | ALDH1A1TSHRKDM4E | |
| SCHEMBL462909 | 0.84 | TSHR (0.34) | ALDH1A1TSHRKDM4E | |
| SCHEMBL2522759 | 0.74 | ALDH1A1 (0.37) | ALDH1A1TSHR | |
| SCHEMBL7679064 | 0.74 | ALDH1A1 (0.37) | ALDH1A1TSHR | |
| SCHEMBL6024966 | 0.74 | GRIK1 (0.47) | ALDH1A1TSHRKDM4E | |
| SCHEMBL5133416 | 0.74 | GRIK1 (0.47) | ALDH1A1TSHRKDM4E | |
| SCHEMBL5133417 | 0.74 | GRIK1 (0.47) | ALDH1A1TSHRKDM4E | |
| SCHEMBL27557763 | 0.73 | ALDH1A1 (0.33) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0912911-A4 | — | — | 1999-06-09 | — | — | EP | claimed |
| EP-0912911-A1 | ACHROMATIC OPHTHALMIC LENSES | INNOTECH, Inc. (US) | 1999-05-06 | — | — | EP | claimed |
| US-5859685-A | Achromatic ophthalmic lenses | INNOTECH, INC. (US) | 1999-01-12 | — | — | US | claimed |
| WO-1998003894-A1 | ACHROMATIC OPHTHALMIC LENSES | INNOTECH, INC. (US) | 1998-01-29 | — | — | WO | claimed |