Trichloroacetic Acid

Trichloroacetic Acid

SCHEMBL8337130

O=C(O)C(Cl)(Cl)Cl.OCCO

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.71
ALDH1A1 P00352 3/20 0.71
TP53 P04637 1/20 0.71
CAMK2A Q9UQM7 1/20 0.33
CYP1A2 P05177 1/20 0.32
CYP2D6 P10635 1/20 0.30
CYP2C19 P33261 1/20 0.30
HIF1A Q16665 1/20 0.30
GPR84 Q9NQS5 1/20 0.30
FFAR1 O14842 1/20 0.30
FFAR4 Q5NUL3 1/20 0.30
OR51E2 Q9H255 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trichloroacetic Acid SCHEMBL9721918 1.00 TSHR (0.71) TSHRALDH1A1TP53CAMK2ACYP1A2
Trichloroacetic Acid SCHEMBL9420645 0.87 TSHR (0.62) TSHRALDH1A1TP53CAMK2A
Trichloroacetic Acid SCHEMBL38661501 0.84
Trichloroacetic Acid SCHEMBL5311061 0.84 TSHR (1.00) TSHRALDH1A1TP53CYP1A2CYP2D6
Trichloroacetic Acid SCHEMBL1331160 0.84
Trichloroacetic Acid SCHEMBL10493657 0.84 TSHR (1.00) TSHRALDH1A1TP53CYP1A2CYP2D6
Trichloroacetic Acid SCHEMBL3220 0.84
Trichloroacetic Acid SCHEMBL1331955 0.84
Trichloroacetic Acid SCHEMBL10745837 0.84
Trichloroacetic Acid SCHEMBL5874935 0.84 TSHR (0.59) TSHRALDH1A1TP53CYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107969730-B Preparation method of tobacco flavor microcapsule 北京亚美方舟科贸有限公司 2020-04-14 CN claimed
CN-107969730-B Preparation method of tobacco flavor microcapsule 北京亚美方舟科贸有限公司 2020-04-14 CN disclosed
US-6001605-A Gro genes CHIRON CORPORATION (US) 1999-12-14 US disclosed
US-5994060-A Gro genes, proteins, and uses thereof CHIRON CORPORATION (US) 1999-11-30 US disclosed
US-5977323-A Method of purifying Gro β or Gro α protein using antibodies CHIRON CORPORATION (US) 1999-11-02 US disclosed
EP-0909817-A1 Uses of gro genes and proteins CHIRON CORPORATION (US) 1999-04-21 EP disclosed
EP-0550661-B1 USES OF GRO GENES AND PROTEINS CHIRON CORP (US) 1999-04-14 EP disclosed
EP-0534978-B1 INTERLEUKIN-1 ANTAGONIST AND USES THEREOF CHIRON CORP (US) 1999-03-24 EP disclosed
US-5874561-A AMINO ACID SEQUENCE OF INTERLEUKIN-1 ANTAGONIST; FOR DIAGNOSIS OF TUMORS AND IMMUNE DISEASES, ANTIARTHRITIC AGENTS, PRETREATMENT AND TREATMENT FOR SEPSIS CHIRON CORPORATION/CHAPEL HILL NORTH CAROLINA (US) 1999-02-23 US disclosed
US-5858688-A Gro genes, proteins, and uses thereof CHIRON CORPORATION (US) 1999-01-12 US disclosed
US-5234839-A Compositions for detecting ras gene proteins and cancer therapeutics CETUS ONCOLOGY CORPORATION (US) 1993-08-10 US disclosed
EP-0550661-A1 GRO GENES, PROTEINS, AND USES THEREOF CHIRON CORPORATION (US) 1993-07-14 EP disclosed
EP-0534978-A1 INTERLEUKIN-1 ANTAGONIST AND USES THEREOF CHIRON CORPORATION (US) 1993-04-07 EP disclosed
EP-0491828-A1 PEPTIDES FROM GTPase-ACTIVATING PROTEIN (GAP), DIAGNOSTIC AND THERAPEUTIC USE THEREOF CHIRON CORPORATION (US) 1992-07-01 EP disclosed
WO-1992006196-A1 GRO GENES, PROTEINS, AND USES THEREOF CETUS ONCOLOGY CORPORATION (US) 1992-04-16 WO disclosed
US-5104975-A Pure, isolated protein which stimulates guanosine triphosphatase in non-oncogenic cells but not in oncogenic mutants CETUS CORPORATION (US) 1992-04-14 US disclosed
EP-0466688-A1 GAP GENE SEQUENCES AND DIAGNOSTIC USES THEREOF. CETUS CORP (US) 1992-01-22 EP disclosed
WO-1991017249-A1 INTERLEUKIN-1 ANTAGONIST AND USES THEREOF CETUS CORPORATION (US) 1991-11-14 WO disclosed
WO-1991002749-A1 PEPTIDES FROM GTPase-ACTIVATING PROTEIN (GAP) AND DIAGNOSTIC AND THERAPEUTIC USE THEREOF CETUS CORPORATION (US) 1991-03-07 WO disclosed
WO-1990000607-A2 GAP GENE SEQUENCES AND DIAGNOSTIC USES THEREOF CETUS CORPORATION (US) 1990-01-25 WO disclosed